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  • 1
    Electronic Resource
    Electronic Resource
    Transport of amines along the visceral nerve of Helix pomatia (1970)
    Springer
    Cell & tissue research 109 (1970), S. 171-179 
    Details
    ISSN: 1432-0878
    Keywords: Nerves ; Transport of Amines ; Helix pomatia ; Granules
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. 20 hours after ligaturing the Helix pomatia visceral nerve there is a marked increase in the level of amine fluorescence proximal to the constriction and a reduction in the level distal to the constriction. 2. Concomitant with the increase in fluorescence, there is an increase in the number of small granular vesicles (30 to 150 nm in diameter) in the nerve fibres proximal to constrictions. At least some of these granules contain amines. 3. Bioassay experiments show that the increase in amine fluorescence is due in part to an increase in the level of 5-hydroxytryptamine. 4. It is concluded that 5-hydroxytryptamine and primary catecholamines are transported, bound to small granules, from the central nervous system along the visceral nerve towards peripheral nerve terminations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00365239
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The blood supply to the central nervous system of Helix pomatia (1970)
    Springer
    Cell & tissue research 111 (1970), S. 160-178 
    Details
    ISSN: 1432-0878
    Keywords: Central nervous tissue ; Blood supply ; Helix pomatia ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. Each paired ganglion of Helix pomatia is supplied by symmetrically arranged branches from the anterior aorta. Capillaries from these branches open into a blood space which is adjacent to, and continuous over the surface of the nervous tissue. Blood passes from this space through the epineural sheath into the body cavity sinuses. 2. With the electron microscope three tissue layers are seen separating the blood spaces from the neurons of each ganglion. These are (i) a luminal endothelium, (ii) a fibrous connective tissue layer which is mainly collagen and (iii) glial cells. 3. Both the luminal endothelium and connective tissue are freely permeable to uncharged particles of 100 Å or less.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00339783
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Uptake of serotonin, 5-hydroxytryptophan and tryptophan by giant serotonin-containing neurones and other neurones in the central nervous system of the snail (Helix pomatia) (1973)
    Springer
    Cell & tissue research 143 (1973), S. 21-35 
    Details
    ISSN: 1432-0878
    Keywords: Central nervous system ; Helix pomatia ; Neurones ; Uptake of serotonin, 5-hydroxytryptophan, tryptophan ; Autoradiography, Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Following exposure to tritiated 5-HTP, silver grains were observed over the perikarya of the GSCs (Giant serotonin cells) of Helix pomatia and other known serotonin-containing neurones in light and electron microscope autoradiograms. There was no indication that the 5-HTP was taken up by nerve endings or by non-nervous structures. The distribution of radioactivity was completely different in autoradiograms of tissue exposed to tritiated serotonin. Silver grains, often in very high concentrations, were observed only over certain fine axon branches and processes thought to be nerve endings. Electron microscope autoradiography showed that these processes contained small dense-cored vesicles, morphologically identical to those thought to sequester serotonin in the perikarya of the GSCs. The accumulation of tritiated tryptophan was less specific; all the neurone perikarya showed an accumulation of radioactivity after exposure to this substance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307448
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Neurosecretion in the vena cava of the cephalopod Eledone cirrosa (1970)
    Springer
    Cell & tissue research 104 (1970), S. 107-115 
    Details
    ISSN: 1432-0878
    Keywords: Cephalopoda ; Eledone ; Neurosecretion ; Ultrastructure ; Cardioaccelerator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. It is thought that the extensive system of nerves passing into the wall of the anterior vena cava in Eledone cirrosa has a neurosecretory function. Examination of the fine structure of the nerve terminations demonstrated the presence of large numbers of electron-dense granules similar to those described in known neurosecretory tissue. 2. Extracts of the anterior vena cava have a persistent excitatory effect on the isolated Eledone heart. The activity is not attributable to 5-hydroxytryptamine, noradrenaline or adrenaline. The active factor is heat stable. The greatest level of activity was found in the inner layers of the vessel in the region where the nerves pass into the wall of the vessel, i.e. the distribution of the active principle parallels that of the nerve terminations in the vein. 3. The physiological role of the system is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340052
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    Paper (German National Licenses)
    Fulltext
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