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  • 1
    Electronic Resource
    Electronic Resource
    Invertebrate Pharmacology (1968)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 8 (1968), S. 273-298 
    Details
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pa.08.040168.001421
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of Synthetic Eledoisin and Bradykinin on Certain Invertebrate Preparations and the Isolated Frog Heart (1966)
    [s.l.] : Nature Publishing Group
    Nature 212 (1966), S. 838-839 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nervous tissue from some rnolluscan species has been shown to contain a potent cardio-excitatory factor other than 5-hydroxytryptamine3'4. This factor has been called substance X. It may be a polypeptide4". It may even be eledoisin. Our experiments were designed to observe the pharmacological ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/212838a0
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  • 3
    Electronic Resource
    Electronic Resource
    Subcellular Localization of Serotonin in an Identified Serotonin-containing Neurone (1970)
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 470-472 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the ganglia of gastropod molluscs are very large neurone somata, some of which contain amines5. We have examined in detail one particularly large serotonin-containing neurone, which is readily located in different preparations, in each cerebral ganglion of the slug Limax maximus. Results of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/225470a0
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  • 4
    Electronic Resource
    Electronic Resource
    THE EFFECT OF OPTIC TENTACLE REMOVAL ON THE TRANSMITTER CONTENT OF THE GIANT SEROTONIN CELL OF HELIX ASPERSA (1972)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 19 (1972), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— There is a giant serotonin-containing neuron in each metacerebral ganglion of the snail Helix pumntia. Much of the amine is localized in small granular vesicles (COTTRELL and OBSORNE, 1970) and evidence for serotonin having a transmitter role in each giant neuron is very strong (COTTRBLL, 1970a, b). It is shown that the content of serotonin in each giant neuron is reduced by ablation of the optic tentacle. Maximum depletion of amine (about 70 per cent) was observed at 6–8 days after the operation. Unilateral depletion followed removal of only one tentacle. To examine the observations more closely, electrophysiological experiments were also made to determine any neuronal connection between the tentacles and the serotonin-containing neurons. No evidence was found for the presence of an axon from either giant neuron in the nerves leading to the tentacles. Stimulation of the nerves supplying the tentacles caused both depolarization and spike firing, and hyperpolarization and inhibition of the giant neurons. It is possible that the depletion of serotonin following ablation of the optic tentacles results from an interruption of the nerve fibres mediating in one or both of the observed types of input.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1972.tb01290.x
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  • 5
    Electronic Resource
    Electronic Resource
    SEROTONIN AND FREE AMINO ACID ANALYSIS OF GANGLIA AND ISOLATED NEURONES OF APLYSIA DACTYLOMELA (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 22 (1974), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —The presence of serotonin and different amino acids was investigated in the ganglia and in isolated giant neurones of Aplysia dactylomela. With a few exceptions the pattern of substances was similar in all the ganglia. Of the many identified neurones studied only one giant neurone located in each cerebral ganglion was found to contain serotonin. GABA was detected in most extracts, including those of the serotonin-containing neurone, known cholinergic, and known neurosecretory neurones. Putrescine, recently detected in extracts of nervous tissue and isolated neurones of Helix, was not detected in Aplysia nervous tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1974.tb06894.x
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  • 6
    Electronic Resource
    Electronic Resource
    Dopamine in an identified neuron of Planorbus corneus (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 22 (1974), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1974.tb06902.x
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  • 7
    Electronic Resource
    Electronic Resource
    FORMATION OF SEROTONIN BY ISOLATED SEROTONIN-CONTAINING NEURONS AND BY ISOLATED NON-AMINE-CONTAINING NEURONS (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 18 (1971), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Isolated giant serotonin-containing neurons of the cerebral ganglia of Helix pomatia were shown to produce serotonin when incubated with 5-hydroxytryptophan (5-HTP) whereas cells of the buccal ganglia, which are non-amine-containing cells did not. The rate of production was comparable to that for Ach in the isolated neurons of Aplysia. The significance of these results is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1971.tb03743.x
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  • 8
    Electronic Resource
    Electronic Resource
    Interpretation of ion cyclotron emission from sub-Alfvénic fusion products in the Tokamak Fusion Test Reactor (1996)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 3 (1996), S. 543-553 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Ion cyclotron emission (ICE) has been observed during neutral beam-heated supershots in the Tokamak Fusion Test Reactor (TFTR) [Phys. Rev. Lett. 72, 3526 (1994)] deuterium–tritium campaign at fusion product cyclotron harmonics. The emission originates from the outer midplane edge plasma, where fusion products initially have an anisotropic velocity distribution, sharply peaked at a sub-Alfvénic speed. It is shown that the magnetoacoustic cyclotron instability, resulting in the generation of obliquely propagating fast Alfvén waves at fusion product cyclotron harmonics, can occur under such conditions. The time evolution of the growth rate closely follows that of the observed ICE amplitude. Instability is suppressed if the fusion products undergo a moderate degree of thermalization, or are isotropic. In contrast, the super-Alfvénic fusion products present in the outer midplane of the Joint European Torus (JET) [Nucl. Fusion 33, 1365 (1993)] can drive the instability if they are isotropic or have a broad speed distribution. This may help to account for the observation that fusion product-driven ICE in JET persists for longer than fusion product-driven ICE in TFTR supershots.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.871881
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  • 9
    Electronic Resource
    Electronic Resource
    The excitation of obliquely propagating fast Alfvén waves at fusion ion cyclotron harmonics (1994)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 1 (1994), S. 1918-1928 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The theory of the magnetoacoustic cyclotron instability, which has been proposed as a mechanism for suprathermal ion cyclotron harmonic emission observed in large tokamaks, is generalized to include finite parallel wave number k(parallel). This extension introduces significant new physics: the obliquely propagating fast Alfvén wave can undergo cyclotron resonant interactions with thermal and fusion ions, which affects the instability driving and damping mechanisms. The velocity–space distribution of the fusion ions is modeled by a drifting ring, which approximates the distribution calculated for the emitting region in tritium experiments on the Joint European Torus (JET) [Cottrell et al., Nucl. Fusion 33, 1365 (1993)]. Linear instability can occur simultaneously at the fusion ion cyclotron frequency and all its harmonics when the fusion ion concentration is extremely low, because the finite k(parallel) gives rise to a Doppler shift, which decouples cyclotron damping due to thermal ions from wave growth associated with fusion ions. Doppler shifts associated with finite k(parallel) may also be related to the observed splitting of harmonic emission lines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.870647
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  • 10
    Electronic Resource
    Electronic Resource
    Determination of experimental tokamak plasma profiles using maximum-entropy analysis (1985)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 984-986 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The diagnostician commonly faces the problem of extracting the maximum information on plasma spatial profiles from only a very limited and noisy data set. Conventionally, functional forms (e.g., a parabola raised to a power) are fitted to the measured data using nonlinear least-squares regression. This immediately biases the interpretation and constrains results to a narrow family of curves for which there may be no real evidence in the data. In this paper, we examine the consequences of abandoning this assumption and, instead, seek the constrained maximum entropy (ME) profile making no such assumptions. Results are compared with conventional analysis. The ME method has the inherent advantages of (i) yielding only positive (and therefore physically meaningful) profiles, (ii) suppression of noise on the data, and (iii) producing a profile which contains the least amount of spurious detail. The method is illustrated with reference to measured chord-average CO2 laser interferometer data taken on the Doublet III tokamak.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138012
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