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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 86 (1981), S. 239-243 
    ISSN: 1437-1596
    Keywords: Shockwave, interaction with nervous tissue ; Impacts of projectiles, shockwaves ; Schockwellen, Auswirkung am peripheren Nerven durch Geschoßeinwirkung ; Geschoßeinwirkung, Schockwellen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Mit Hilfe eines ausführlich dargestellten Versuchsaufbaues wird gezeigt, daß durch Geschoßeinwirkung entstehende sogenannte Schockwellen an peripheren Nerven Summenaktionspotentiale (CAP) ausgelöst werden können. Die Amplitude des CAP steigt zunächst mit zunehmendem Schockwellendruck an, erreicht aber dann eine Sättigung bei ca. 8 bar. Der Nerv zeigt keine elektrische Aktivität unterhalb einer Schockwellenamplitude von 0,75 bar.
    Notes: Summary To verify a presumed interaction between shockwaves arisen by impacts of high velocity projectiles and nervous tissue an electrophysiological experiment is performed with the following results: In peripheral nerves regular compound action potentials (CAPs) are provoked by shockwaves the amplitudes of which are increased corresponding to the pressure intensity of the shockwaves. The nerve shows no electrical activity below a certain pressure threshold (0.75 bar). Saturation of the CAP amplitude occurs beyond a pressure limit of 8 bar.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-1596
    Keywords: Key words Ganglion cells ; Hippocampus ; Immunohistochemistry ; Mean optical density (MOD) ; Morphine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract To investigate the topography of morphine distribution in the human brain, a method has been developed to detect morphine immunohistochemically. In this study hippocampus tissue from victims of heroin overdose (blood morphine concentrations 220 ng/g–1500 ng/g; 6-MAM positive urine sample), known for its high concentration of μ-opiate receptors was used. The immunohistochemical staining was performed with an anti-morphine antiserum originally developed for radio-immuno-assays. In comparison with control specimens from cases of sudden death without morphine exposition or a history of heroin abuse, the brains from victims of heroin overdose showed selectively stained ganglion cells, axons and dendrites, suggesting a massive concentration of morphine in the neuronal structures.
    Type of Medium: Electronic Resource
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