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  • Organic Chemistry  (3)
  • Inorganic Chemistry  (2)
  • Ultrastructure  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Ultrastructural changes of bone marrow in canine cyclic hematopoiesis (CH dog) (1981)
    Springer
    Virchows Archiv 390 (1981), S. 93-108 
    Details
    ISSN: 1432-2307
    Keywords: Cyclic hematopoiesis ; Bone marrow ; Ultrastructure ; Nuclearcytoplasmic asynchrony ; Döhle-like bodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathogenesis of cyclic hematopoiesis (CH) in the grey collie dog is still unknown. It has been proposed that periodic bursts of necrosis of the bone marrow neutrophils would induce cyclic arrests of the stem cell differentiation. In the present study, the sequential changes undergone by the erythroid and neutrophil series of the bone marrow of CH dogs were evaluated by electron microscopy. Erythroid cells presented quantitative periodic oscillations but the morphologic features of both immature and mature cells were normal. On the contrary, nonspecific necrotic changes were observed to occur in the myeloid series. Those abnormalities, which were more marked between days 9 and 11 of the cycle, mainly involved the immature cells and, to a lesser extent, the mature neutrophils. The number of necrotic cells was variable in different cycles, but always represented a small portion of the myeloid cells. In addition, few bone marrow macrophages displayed signs of phagocytic activity containing cell debris. The ultrastructural changes of the myeloid series were accompanied by an abnormal decrease of peroxidase activity and the permanence of large acid phosphatase-positive Golgi complexes in mature neutrophils, as defined by morphologic criteria. Döhle-like arrays of rough endoplasmic reticulum were present in many cells. Our findings suggest that an asynchronic development of myelocytes occurs as a result of regulatory abnormalities related to the congenital defect of the bone marrow which interferes with the differentiation and maturation of the stem cells. Necrosis in some myeloid cells would be a secondary phenomenon rather than a causal factor for the cyclic arrest of cell maturation as has been previously submitted. Furthermore, the small size of the necrotic cell population could not justify the production of “inhibitors” in sufficient amounts as to block the normal evolution of the bone marrow stem cell pool.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00443900
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  • 2
    Electronic Resource
    Electronic Resource
    Kristallographische Interpretation der Feinstruktur der B-Granula in den Langerhansschen Inseln der Ringelnatter, Natrix n. natrix (L.) (1972)
    Springer
    Cell & tissue research 131 (1972), S. 559-570 
    Details
    ISSN: 1432-0878
    Keywords: Islets of Langerhans ; Grass-snake ; Crystalline B-granules ; Ultrastructure ; Crystallography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Kristalline B-Granula im Pankreas der Ringelnatter besitzen die Form von Rhombendodekaedern (a ≈ 11 nm, kubisch-raumzentriertes Gitter). Diese Diagnose wird abgeleitet von den Ergebnissen der dreidimensionalen Rekonstruktion von Serienschnitten, der optischen Diffraktometrie und aus dem Vergleich mit Kristallmodellen. Die Bedeutung kristalliner B-Granula wird erörtert.
    Notes: Summary Crystalline B-granules of grass-snake islets of Langerhans have been shown to possess the shape of rhombic dodecahedra (a ≈ 11 nm, cubic body-centered lattice). Three-dimensional reconstructions from serial sections, optical diffractometry and comparison with crystal models were the techniques utilized. The significance of crystalline B-granules is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306971
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  • 3
    Electronic Resource
    Electronic Resource
    Synthese von kristallin-flüssigen Verbindungen. I. n-Alkyl- und n-Alkoxyderivate des 3-Hydroxy-2,5-diphenyl-pyrazins (1966)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 33 (1966), S. 265-276 
    Details
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es werden die Synthesen von 2 homologen Reihen des 3-Hydroxy-2,5-diphenyl-pyrazins und 2-Benzoyl-4(5)-phenyl-imidazols beschrieben. p-n-Alkyl- und p-n-Alkoxyphenylglyoxal-hydrate kondensieren unter ammoniakalischen Bedingungen bevorzugt zu den entsprechenden Imidazolylketonen und nur in geringen Ausbeuten zu Hydroxypyrazinen. Die Alkylhomologen des Pyrazins schmelzen ab Äthylderivat zu kristallin-flüssigen Phasen auf, die dem smektischen Typ angehören. Mit wachsenden Flügelgruppen treten Umwandlungspunkte in diesen Phasen auf. Die beiden ersten Glieder der Ätherreihe haben zusätzlich einen nematischen Bereich. Allen Imidazolylketonen fehlen diese Eigenschaften. Der Einfluß der α-ständigen Hydroxygruppe am heterocyclischen Mittelstück der gestreckten Molekeln wird diskutiert.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19660330508
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  • 4
    Electronic Resource
    Electronic Resource
    Dienoligomerisierung. XVII. Nickelkomplexkatalysierte Codimerisierung von isomeren Octatrienen mit PropenDiese Untersuchungen wurden von September 1974 bis Juni 1975 an der Sektion Verfahrenschemie der Technischen Hochschule „Carl Schorlemmer“ Leuna-Merseburg durchgeführt. (1980)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 322 (1980), S. 663-668 
    Details
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dienoligomerization. XVII. Catalytic Codimerization of Isomeric Octatrienes with Propene by Nickel-ComplexesCodimerizations of isomeric n-octa-1,3c,t,7-triene 1, n-octa-1,3c,6t-triene 2 and 3-methylhepta-1,4t,6-triene 3 with propene 4 in the presence of cationic tetrakis-(triethylphosphite)-nickelhydride complex to form 4-methyldeca-1,5t,9-triene 6, 4-isopropenylocta-2c,7-diene 10, 4-methyldeca-1,5t,8t-triene 12, 4-isopropenylocta-2c,6t-diene 16, 3,6-dimethylnona-1,4t,7c,t-trienes 17, 2,3,6,-trimethylocta-1,4t,7-triene 19 and 3-methyl-4-isopropenylhepta-1,5c-diene 22.The influence of the temperature on the reaction and a reaction mechanism is discussed.No codimers from octatrienes and isobutene were formed under the conditions of this work.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19803220419
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  • 5
    Electronic Resource
    Electronic Resource
    Dienoligomerisierung. XVI. Nickelkomplexkatalysierte Codimerisierung von isomeren Octatrienen mit EthenDiese Untersuchungen wurden in der Zeit von September 1973 bis Juli 1975 an der Sektion Verfahrenschemie der TH „Carl Schorlemmer“ Leuna-Merseburg durchgeführt. (1980)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 322 (1980), S. 655-662 
    Details
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dienoligomerization. XVI. Catalytic Codimerization of Isomeric Octatrienes with Ethene by Nickel ComplexesThe isomeric octatrienes (n-octa-1,3c,t,7-triene 1, n-octa-1,3c,6t-triene 2 and 3-methylhepta-1,4t,6-triene 3), which are easily obtained in high yields by transition metal catalysed dimerization of butadiene, react with ethene 4 in the presence of the cationic tetrakis-(triethylphosphite)-nickelhydride complex 5 to the dodimers 3-methylnona-1,4c,t,8-triene 6, 4-vinylocta-2c, 7-diene 7, 3-methyl nona-1,4c,t,7t-triene 8, 4-vinylocta-2c,6t-diene 9, 3,6-dimethylocta-1,4c,t,7-triene 10 and 3-methyl-4-vinylhepta-1,5c-diene 11. The concentration-time dependence and a possible reaction mechanism of the codimerization are discussed and the structure data of the reaction products are reported.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19803220418
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  • 6
    Electronic Resource
    Electronic Resource
    Ueber Oxycuminsäure (1880)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 13 (1880), S. 1660-1664 
    Details
    ISSN: 0365-9496
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.188001302104
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  • 7
    Electronic Resource
    Electronic Resource
    Ueber Condensation tertiärer Basen mittelst Stickoxyd (1880)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 13 (1880), S. 2136-2141 
    Details
    ISSN: 0365-9496
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.188001302207
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