ISSN:
1432-0584
Keywords:
Intestinal iron absorption
;
Hypoxia
;
Mucosal transferrin
;
Iron binding proteins
;
Erythropoiesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Three days hypoxia (0.5 atm) increased the haemoglobin and haematocrit values in rats paralleled by enhanced intestinal iron absorption. The destination of recently-absorbed iron was primarily the erythropoietic system, viz. bone marrow, spleen and red cells. Total plasma transferrin, was increased by 30%, but no significant changes in mucosal transferrin were found. No increase in labelling of mucosal transferrin by absorbed iron was observed. These results suggest that mucosal transferrin does not play a major role in the regulation of intestinal iron absorption in hypoxia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00367458
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