Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Longitudinal smooth muscle in pulmonary arteries (1984)
    Springer
    Virchows Archiv 404 (1984), S. 265-274 
    Details
    ISSN: 1432-2307
    Keywords: Pulmonary arteries ; Intimal thickening ; Intimal smooth muscle ; Congenital heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In lung biopsy specimens of 19 patients with congenital heart disease and pulmonary hypertension, in addition to the common features of plexogenic arteriopathy, longitudinal smooth muscle cells were found in small pulmonary arteries. These cells were arranged in bundles or layers, particularly in the intima but sometimes within the media or adventitia of the arteries. They often caused severe narrowing of the lumen. Corrective surgery of the cardiac defect was performed in 14 patients. The results suggested that even when these changes are wide-spread and severe, they do not stand in the way of a favourable postoperative course. In one patient who underwent a banding procedure of the pulmonary artery, virtually complete regression of the smooth muscle layers could be demonstrated in a second biopsy, taken 5 years later during a corrective operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00694892
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    A stable model of respiratory distress by small injections of oleic acid in pigs (1996)
    Springer
    Intensive care medicine 22 (1996), S. 336-344 
    Details
    ISSN: 1432-1238
    Keywords: Key words Oleic acid ; Lung injury ; Respiratory distress ; Albumine ; Bolus injections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   Objective: Development of a stable model of respiratory distress in pigs with oleic acid, fulfilling clinical criteria of the adult respiratory distress syndrome (ARDS). Design: Eight pigs (9.1±0.7 kg) were anesthetized with pentobarbital, paralyzed with tubocurarine and mechanically ventilated with an FIO2 of 0.6, an I:E ratio of 2:3 and a PEEP of 0.2 kPa. Oleic acid (dissolved 1:1 in 96% alcohol) was administered in a series of multiple injections of 0.1 ml until P aO2 was lower than 8 kPa. Measurements and results: Careful titration of the oleic acid injections on guidance of the P aO2 established a reproducible respiratory distress (P aO2=7.3±0.8 kPa), in which gas exchange and hemodynamic variables were stable for at least 4 h. The number of oleic acid injections (22±11, mean and SD) varied between the animals. Conclusions: With the use of multiple injections of oleic acid, a stable model of early respiratory distress in pigs can be achieved, in spite of individual differences in sensitivity. Such a stable model allows for a diversity of studies on early respiratory distress.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01700456
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...