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  • Polymer and Materials Science  (3)
  • K+ conductance  (2)
  • Lichen sclerosus et atrophicus  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Amelanotic malignant melanoma of the vulva (1996)
    Springer
    Archives of gynecology and obstetrics 259 (1996), S. 45-50 
    Details
    ISSN: 1432-0711
    Keywords: Key words: Amelanotic melanoma ; Vulvar neoplasms ; Lichen sclerosus et atrophicus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We report on a 60 year old patient with a 6 month history of vulval pruritus and an erosive vulval lesion which was mistaken for lichen sclerosus et atrophicus. Histologically the diagnosis of an amelanotic malignant melanoma of the vulva was established. We review the literature about this rare malignant tumor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004040050134
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  • 2
    Electronic Resource
    Electronic Resource
    Amelanotisches Melanom der Vulva unter dem klinischen Bild eines „Lichen sclerosus et atrophicus“ (1996)
    Springer
    Der Hautarzt 47 (1996), S. 854-857 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Vulvaneoplasie ; Amelanotisches malignes Melanom ; Lichen sclerosus et atrophicus ; Key words Vulvar neoplasia ; Amelanotic malignant melanoma ; Lichen sclerosus et atrophicus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Malignant melanoma of the vulva is an uncommon disease. The amelanotic subtype is only rarely mentioned. We report a 60-year-old patient with a 6 month history of vulvar pruritus. Ivory lesions combined with erosions and fine `cigarette paper' – like wrinkling were suspicious for lichen sclerosus et atrophicus. Histologically the diagnosis of an amelanotic malignant melanoma was made. Amelanotic melanoma may present with a wide variety of clinical features. Even in the uncommon location of the vulva, amelanotic melanoma should be suspected in any nonhealing nonpigmented lesion.
    Notes: Zusammenfassung Das maligne Melanom der Vulva ist ein sehr seltener Tumor. Die amelanotische Variante ist nur in wenigen Fällen in der Literatur beschrieben. Wir berichten über eine 60jährige Patientin, die sich mit einer chronisch nässenden Vulvaläsion vorstellte. Die weißlichen Herde in Verbindung mit Erosionen und teilweise zigarettenpapierartiger Fältelung der Haut ließen klinisch v.a. an einen Lichen sclerosus et atrophicus denken. Histologisch zeigte sich ein amelanotisches malignes Melanom. Mit unserer Fallbeschreibung möchten wir ein weiteres Beispiel geben für die große morphologische Vielfalt des amelanotischen malignen Melanoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050520
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  • 3
    Electronic Resource
    Electronic Resource
    Chloride transport in the diluting segment of the K+ adapted frog kidney: Effect of amiloride and acidosis (1986)
    Springer
    Pflügers Archiv 407 (1986), S. S60 
    Details
    ISSN: 1432-2013
    Keywords: Amiloride ; Cl− transport ; Diluting segment ; K+ conductance ; Adaptation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The hypothesis was tested whether amiloride and/or an acute acid load influence Cl− transport in the diluting segment of the isolated-perfused kidney of the K+ adapted frog (rana pipiens). Transepithelial resistance (luminal cable analysis) and Cl− net flux (Cl− sensitive microelectrodes) were evaluated at various concentrations of amiloride, at highpCO2 or low HCO 3 − in the kidney perfusate. Amiloride or an acute acid load increase transepithelial resistance. The resistance-change at given concentrations of amiloride is markedly enhanced under static head conditions, i. e. at low luminal NaCl concentrations. Amiloride or acidosis (highpCO2) reduce Cl− net reabsorption; combination of both potentiates this inhibitory effect. We conclude: an acute acid load acidifies the cell cytosol. This effect is aggravated dramatically after amiloride-induced inhibition of the luminal Na+/H+ exchanger. The luminal pH-sensitive K+ conductance decreases. This results in a depolarization of the cell membranes. Consequently, the peritubular electrochemical driving force for the exit step of Cl− (from cell to blood) dissipates. Therefore, Cl− net reabsorption is blunted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00584931
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  • 4
    Electronic Resource
    Electronic Resource
    Fused cells of frog proximal tubule: I. Basic membrane properties (1987)
    Springer
    The journal of membrane biology 100 (1987), S. 43-51 
    Details
    ISSN: 1432-1424
    Keywords: frog kidney ; proximal tubule ; HCO 3 − transport ; K+ conductance ; Cl− conductance ; fusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Proximal tubular cells of the frog (Rana esculenta) kidney were fused within an isolated tubule portion to giant cells according to the polyethylene-glycol fusion method. Cell membrane potentials (V m ) were measured while cells were superfused with varioús experimental solutions. Rapid concentration stepchanges of different ions allowed to calculate the respective transference numbers (t ion). In some experiments the specific cell membrane resistances (R m ) were evaluated by measuringV m induced by short current pulses injected into the cell with a second electrode. The experiments reveal: i) Fused cells of the proximal tubule exhibit aV m of −49.5±1.6 mV (n=65). ii) Addition of glucose to the perfusate yields a transient depolarization, consistent with a rheogenic Na/glucose cotransport system. iii) In absence of organic substrates the whole cell membrane conductance is made up of K+ and HCO3, iv) There is a positive relationship betweenV m andtK+ and a negative relationship betweenV m andtHCO 3 − . v) HCO 3 − -inducedV m changes are attenuated or abolished when Na+ is replaced with choline+, consistent with a rheogenic Na+/HCO 3 − cotransport system. vi) Replacement of Na+ by choline+ depolarizesV m and increasesR m by about 50%; addition of 3 mmol/liter Ba2+ to the Na+-free perfusate increasesR m by about 58% compared to the initial control value. vii) There is no measurable cell membrane Cl− conductance. We conclude that fused cells of proximal tubule exert both luminal and peritubular membrane properties. In absence of organic substrates the cell membrane potential is determined by the HCO 3 − and K+ transport systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02209139
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  • 5
    Electronic Resource
    Electronic Resource
    Diffusionssperrschichten aus Al2O3 zur Beeinflussung der Haftschichtoxidation von MCrAlY-Legierungen (1992)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 43 (1992), S. 492-495 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Diffusion barriers of Al2O3 to reduce the bondcoat-oxidation of MCrAlY alloysUnder operating conditions in gas turbines plasma sprayed MCrAlY bondcoats (M = Co and/or Ni) for thermal barrier coatings are exposed to a strong oxidation attack. One possibility to reduce bondcoat oxidation is the application of diffusion barriers. Onto the bondcoat, diffusion barriers of Al2O3 are deposited by CVD, PVD and plasma pulse process. The oxidation behaviour of these coating systems were examined at a temperature of 1273 K for times up to 250 hours.The CVD and PVD Al2O3-coated specimen show compared to the uncoated specimens smaller oxidation rates. The porous Al2O3 coatings, produced by plasma pulse process are not fit for oxidation protection of the bondcoat. There is hope for further improvement of the oxidation resistance by optimizing the CVD- and PVD- process parameters.
    Notes: MCrAlY-Haftschichten (M = Co und/oder Ni) für keramische Wärmedämmschichten sind bei Betriebsbedingungen einem starken Oxidationsangriff ausgesetzt. Eine Möglichkeit, die Haftschichtoxidation zu verringern, besteht in der Verwendung von Diffusionssperrschichten. Auf die Haftschicht werden Diffusionssperrschichten aus Al2O3 mittels CVD, PVD und Plasma-Puls-Verfahren aufgebracht und einer isothermen Oxidationsbelastung (T = 1273 K, t = 250 h) bei atmosphärischen Bedingungen unterworfen.Die PVD- und CVD-beschichteten Haftschichtproben weisen gegenüber unbeschichteten Proben stark reduzierte Oxidationsraten auf. Ein weiters Optimierungspotential des PVD- und CVD-Verfahrens scheint vorhanden. Das Plasma-Plus-Verfahren ist aufgrund der damit erhaltenen porösen Schicht zum Aufbringen des Oxidationsschutzes ungeeignet.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19920431005
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  • 6
    Electronic Resource
    Electronic Resource
    Bestimmung des C=O—Gruppengehalts in anoxydierten cellulosehaltigen Materialien und vorbehandeltem Polyäthylen (1971)
    Weinheim : Wiley-Blackwell
    Angewandte Makromolekulare Chemie 19 (1971), S. 57-64 
    Details
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: The carbonyl group concentration was determined with C-14 labelled 2,4-dinitrophenylhydrazine in the following substances: pergamin, filterpaper, cellophane, polyethylene and polypropylen. For standardizing the method, the MALAPRADE-splitting of the C2—C3-bond in the glucosidic unit of celluloses was used. The reactivity towards NaJO4 increased in the following way: cellophane 〈 filterpaper 〈 pergamin.
    Notes: An Hand von Pergamin, Filterpapier und Cellophan sowie Polyäthylen und Polypropylen wird eine Methode zum Nachweis der Carbonylgruppenkonzentration mit Hilfe von C-14 markiertem 2,4-Dinitrophenylhydrazin aufgezeigt. Zur Standardisierung der Methode wurde die MALAPRADE-Spaltung der C2—C3-verknüpfung in der glucosidischen Einheit der Cellulose herangezogen. Die Reaktionsfähigkeit gegenüber NaJO4 steigt in folgender Reihenfolge an: Cellophan 〈 Filterpapier 〈 Pergamin.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/apmc.1971.050190104
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  • 7
    Electronic Resource
    Electronic Resource
    Cellulosepfropfung mit vinylmonomeren (1969)
    Weinheim : Wiley-Blackwell
    Angewandte Makromolekulare Chemie 8 (1969), S. 153-166 
    Details
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: The reactivity of vinyl monomers V-XIV and cellulose (beach sulfit pulp, filter paper) shows an optimum depending on the use of peroxide (I-IV) or ionic type catalysts (TiCl4, Fe3+, Ce4+) and their concentrations. The swelling degree in various systems of inclusion agents (H2O/NaOH, LiOH, KOH/CH3OH/CH3COCH3/C6H6) which must be properly chosen with respect to the used monomer, or in the monomers, in their mixtures and mixtures of monomers with solvents is of dicisive importance for a positive course of the reaction, for its yield and velocity.The obtained grafted products have modified properties in comparison with non grafted cellulose and, according to the type of the grafting monomers and the reaction conditions, they form a wide series from brash, brittle, hard, water repellent products to adsorbent, weldable and strong cracking resistent materials.
    Notes: Die Reaktionsbereitschaft der Vinylmonomeren V-XIV mit Cellulose (Buchensulfitzellstoff, Filterpapier) zeigt ein Optimum in Abhängigkeit von peroxidischen (I-IV) oder ionischen Katalystoren (TiCl4, Fe3+, Ce4+) und deren Konzentrationen. Von entscheidender Bedeutung für den positiven Verlauf der Pfropfreaktion sowie deren Ausbeute und Geschwindigkeit ist der Quellungsgrad in verschiedenen Inclusionssystemen (H2O/NaOH, LiOH, KOH/CH3OH/CH3COCH3/C6H6), die spezifisch auf das Monomere abgestimmt sein müssen, oder in den Monomeren, Monomergemischen oder Monomer-Lösungsmittel-Gemischen.Die erhaltenen Pfropfprodukte zeigen gegenüber der ungepfropften Cellulose modifizierte Eigenschaften, die je nach Art des Pfropfmonomeren und der Reaktionsbedingugen variierbar sind von brüchig, spröde, hat, hydrophob bis stark saugfähig, schweißbar und reißfest.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/apmc.1969.050080111
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