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  • Key words: Bile duct stones — Laparoscopic cholecystectomy — Endoscopic sphincterotomy — High-risk patient — Elderly  (1)
  • bio-inspired VLSI circuits  (1)
  • regularization  (1)
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  • 1
    ISSN: 1432-2218
    Keywords: Key words: Bile duct stones — Laparoscopic cholecystectomy — Endoscopic sphincterotomy — High-risk patient — Elderly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The best approach to bile duct stones in high-risk patients is controversial. We showed in a randomized trial that open surgery had a morbi-mortality similar to that of endoscopic sphincterotomy alone (ES) and less late biliary complications. The aim of this study was to evaluate a minimally invasive approach to duct stones in high-risk patients compared with open surgery or ES alone. Methods: Sixty high-risk patients (mean age 80 years) suspected of duct stones were treated by ES + laparoscopic cholecystectomy (LC). High-risk factors were: age 〉 70 years, Goldman cardiac index 〉 13, chronic pulmonary disease, liver cirrhosis, neurologic deficit, and severe obesity. Results: ERCP success was 87%. Duct stones were found in 75%. LC succeeded in 92%. Post-LC stay was 4 days. Overall morbidity was 19% and mortality was 3%. Recurrent symptoms (mean follow-up: 9 months) was 3.6%. When compared with open surgery or ES alone, ES + LC had a similar morbi-mortality, but shorter postop stay (p 〈 0.001). Late symptoms appeared in 20% after ES alone vs 4% after open surgery or ES plus LC (p 〈 0.04). Conclusions: Combined ES + LC is an effective alternative to open surgery or ES alone for treatment of duct stones in high-risk patients.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neural processing letters 12 (2000), S. 107-113 
    ISSN: 1573-773X
    Keywords: backpropagation ; regularization ; multilayer perceptron ; fault tolerance ; mean square sensitivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract When the learning algorithm is applied to a MLP structure, different solutions for the weight values can be obtained if the parameters of the applied rule or the initial conditions are changed. Those solutions can present similar performance with respect to learning, but they differ in other aspects, in particular, fault tolerance against weight perturbations. In this paper, a backpropagation algorithm that maximizes fault tolerance is proposed. The algorithm presented explicitly adds a new term to the backpropagation learning rule related to the mean square error degradation in the presence of weight deviations in order to minimize this degradation. The results obtained demonstrate the efficiency of the learning rule proposed here in comparison with other algorithm.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Analog integrated circuits and signal processing 13 (1997), S. 111-121 
    ISSN: 1573-1979
    Keywords: bio-inspired VLSI circuits ; spike processing neurons ; temporal interactions ; address-driven communication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The paper presents a VLSI approach to approximate thereal-time dynamics of a neuron model inspired from the classicalmodel of Hodgkin and Huxley, in which analog inputs and outputsare represented by short spikes. Both the transient and the steady-statebehaviours of these circuits depend only on process-independentlocal ratios, thus enabling single or multiple-chip VLSI implementationsof very large analog neural networks in which parallelism, asynchronyand temporal interactions are kept as important neural processingfeatures. Measurements on an integrated CMOS prototype confirmexperimentally the expected electrical and temporal behavioursof the proposed neural circuits and illustrate some outstandingfunctional features of the neural model: spike-mediated modulationof the neural activity, self-regulation of the total activityin neural groups, and emulation of temporal interaction mechanismswith well controlled time constants at different scales.
    Type of Medium: Electronic Resource
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