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  • Key words: Breast  (1)
  • Key words: Computer tomography  (1)
  • 1
    ISSN: 1432-1084
    Keywords: Key words: Computer tomography ; Oral contrast medium ; Iopentol ; Amidotrizoate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. The aim of the trial was to evaluate and compare the safety and efficacy of iopentol (Imagopaque®, Nycomed Imaging AS, Oslo, Norway) and amidotrizoate (Peritrast®, Köhler Pharma, Alsbach, Germany), both 300 mg I/ml initially, but diluted to 2 % (v/v) and administered orally. Sixty-four and 65 patients were included in the respective contrast medium groups. Portions of contrast medium, totally 1.5 l, were taken every 15 min during the hour before the examination. A standard radiological procedure for abdominal CT was followed. Nine percent of the patients in each group experienced adverse events which were possibly contrast medium related. Taste acceptance was comparable in the two groups. Except for the stomach, radiographic efficacy was satisfactory for all intestinal segments. The difference in density in the proximal small bowel (main parameter) achieved with the media was not significant (p = 0.33), nor was that as regards image homogeneity (contrast distribution). In conclusion, iopentol is well suited for oral contrast enhancement of the gastrointestinal tract in abdominal computed tomography.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Breast ; Parenchymal pattern ; MR imaging ; Contrast enhancement ; MR mammography ; Menstruation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Magnetic resonance mammography (MRM) provides data regarding the nature of tumours based on contrast medium dynamics; fibrocystic changes in the breast, however, may lead to false-positive results. This study investigated whether the contrast medium dynamics of fibrocystic changes are dependent on the menstrual cycle. Twenty-four patients with palpable lumps but normal mammographies and ultrasound studies were examined. The MRM technique was performed during the first and second part of the menstrual cycle using a FLASH 3D sequence, both native and at 1, 2, 3 and 8 min after intravenous application of 0.15 mmol/kg body weight of gadodiamide. The calculated time–intensity curves were evaluated based on the following criteria: early percentage of contrast medium uptake in relation to the native value; formation of a plateau phenomenon after the second minute; the point of maximal contrast medium uptake; and calculation of the contrast enhancing index. During the second half of the menstrual cycle, a generally greater contrast medium uptake was observed. Nevertheless, when further diagnostic criteria, such as continuous contrast medium increase as a function of time, were considered, there was no increased rate of false-positive findings. The phase of the menstrual cycle may affect the specificity of the examination, if only the quantitative contrast medium uptake and the percentage of contrast medium uptake in the first 2 min are considered. A control MRM during the other half of the cycle may then be indicated and additional diagnostic criteria may improve specificity.
    Type of Medium: Electronic Resource
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