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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 143 (1985), S. 261-268 
    ISSN: 1432-1076
    Keywords: Apnea ; Sleep state ; Polygraphic monitoring ; Preterms ; SIDS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract By means of polygraphic sleep recording, the sleep apnea profile with respect to the number and duration of inactive, obstructive and mixed apneic episodes as well as periodic breathing has been investigated in infants born preterm at 40, 52 and 64 weeks conceptional age and compared to that of term infants. At 40 weeks preterm infants showed significantly more apnea and periodic breathing compared to term infants. The difference was essentially due to obstructive and mixed apnea in non-REM sleep. There was a sharp decrease in all apneic variables—inactive, obstructive and mixed apnea as well as of periodic breathing—at 52 weeks conceptional age in infants that were previously preterm. Both groups exhibited a rather identical sleep apnea profile at 64 weeks. Two prospectively studied infants in the preterm group later became SIDS victims. One of them might have been identified as being at risk on the basis of his apnea profile compared to the normative data now available.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-0474
    Keywords: Schlüsselwörter ; Zentrales anticholinerges Syndrom ; Engelstrompete ; Datura suaveolens ; Skopolaminvergiftung ; Alkaloidintoxikation ; Key words ; Central anticholinergic syndrome ; Angel’s trumpet ; Datura suaveolens ; Scopolamine-poisoning ; Alkaloid-intoxication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Reports of accidental alkaloid-intoxications with plants of the nightshade family, in particular Datura-species are well known in pediatric care. The intentional abuse as a hallucinogenic drug in adolescents became more frequent in recent years. Two patients, a 14- resp. 16-year old boy were admitted to the intensive care units of our hospitals because of a severe central anticholinergic syndrome after ingestion of tea from Angel’s Trumpet blossoms for experimental reasons. Patient’s history in the first somnolent patient was not available at the time of admission, a routine immunological drug screening of the patient’s urine had been negative. Discussion: Prominent central nervous symptoms as unconsciousness or hallucinations in adolescents without further explanation should suggest a special toxicological analysis for tropan-alcaloids e.g. scopolamine because of increasing abuse of plants containing the drug.
    Notes: Zusammenfassung Akzidentelle Intoxikationen von Nachtschattengewächsen bei Kindern sind bereits häufiger beschrieben worden. In jüngster Zeit nimmt der bewußte Mißbrauch insbesondere von Daturaarten als Rauschmittel bei Heranwachsenden deutlich zu. Wir berichten über 2 14 bzw. 16jährige Jugendliche, die aus Experimentierfreudigkeit einen Tee aus Engelstrompetenblüten getrunken hatten und sich wegen eines ausgeprägten zentralen anticholinergen Syndroms auf unseren Intensivstationen behandeln lassen mußten. Im ersten Fall, einem somnolenten Patienten, war zunächst keine Anamnese verfügbar, ein immunologisches Drogen-Screening im Urin blieb ohne richtungsweisendes Ergebnis. Diskussion: Auch bei im Vordergrund stehender Bewußtseinstrübung oder paranoid-halluzinatorischen Symptomen sollte insbesondere bei Jugendlichen an eine Ingestion von Tropanalkaloiden bzw. eine Skopolaminintoxikation durch Ziergewächse wie Engelstrompete oder Stechapfel gedacht und gezielt danach gesucht werden.
    Type of Medium: Electronic Resource
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