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  • Key words P-VEP • Pituitary • Adenoma • Electrophysiology  (1)
  • Keywords Intracranial pressure  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 16 (2000), S. 451-456 
    ISSN: 1433-0350
    Keywords: Keywords Intracranial pressure ; CSF dynamics ; Infusion test ; Rat ; H-Tx rat ; Outflow resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Although the hydrocephalic H-Tx rat is a widely used model, data on the cerebrospinal fluid (CSF) dynamics in hydrocephalic rats are rare or – as the pressure volume index (PVI) – not available. We used hydrocephalic and nonhydrocephalic H-Tx rats, a stock with a high percentage of inherited hydrocephalus, for the evaluation of such data. In addition, a new, simple mathematical algorithm (”dynamic infusion test”), which has not formerly been used in animal experiments, was used as a pathophysiological model of CSF dynamics. Compared with classical methods for evaluation of these data, the dynamic infusion test gives a deeper insight into the relation between ICP and CSF dynamics. It was found that the resistance to outflow (ROF) in hydrocephalic rats was at least twice that in nonhydrocephalic rats. The PVI measured was similar in hydrocephalic and nonhydrocephalic animals, but clearly higher than the values reported in the literature. This may be attributable to the fact that the classically used bolus test, in contrast to the ”dynamic infusion test”, is representative only for the CSF compartment which is directly exposed to the bolus application.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Ophthalmologe 95 (1998), S. 28-32 
    ISSN: 1433-0423
    Keywords: Key words P-VEP • Pituitary • Adenoma • Electrophysiology ; Schlüsselwörter Muster-VEP • Hypophyse • Adenom • Elektrophysiologie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Fragestellung: Hypophysenadenome sind Tumoren der Sellaregion, die zu einer Kompression des Chiasma opticum führen können. Augenärztliche Untersuchungen stellen somit einen wichtigen Bestandteil der perioperativen Betreuung dieser Patienten dar. Patienten und Methode: Neben den klassisch ophthalmologischen Untersuchungsmethoden des bestkorrigierten Fernvisus und der Gesichtsfelduntersuchung verwandten wir die elektrophysiologische Methode der Muster-visuell evozierten Potentiale (M-VEP), um den perioperativen Verlauf nach durchgeführter transphenoidaler Resektion kontrollieren zu können. Ergebnisse: Die N75–P100-Amplitude des M-VEP erwies sich als sensitivster Marker zum Nachweis einer postoperativen Erholung. Es kommt nach durchgeführter Operation zu einem signifikanten Anstieg dieser Amplitude, wobei die P100-Latenzzeit sowie der Fernvisus und der Gesichtsfeldbefund keine signifikante Änderung zeigen. Schlußfolgerung: Das Muster-VEP stellt eine wichtige Ergänzung zur Verlaufskontrolle bei Erkrankungen mit der Gefahr der Optikuskompression dar.
    Notes: Background: Pituitary tumors are adenomas of a region of the sella turcica which can produce compression of the anterior visual pathway. Patients and methods: Besides clinical signs of visual improvement such as enhanced visual acuity and visual field, the use of electroophthalmological methods can help monitor patients after neurosurgery. Results: The N75 P100 amplitude of the p-VEP has proven to be the most sensitive marker for measuring-improvements after surgery. This amplitude significantly increased, whereas latency time, visual acuity and visual field showed no statistically significant changes after surgery. Conclusions: The p-VEP is an important tool in treating patients with compression of the visual pathway.
    Type of Medium: Electronic Resource
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