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  • Key words Pediatric dermatology  (1)
  • Methotrexate  (1)
  • Regulation of granulopoiesis  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 52 (1986), S. 165-168 
    ISSN: 1432-0584
    Keywords: Spontaneous remission ; Acute leukemia ; Prognostic factors ; Regulation of granulopoiesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A patient with acute myelomonocytic leukemia who experienced a spontaneous remission, is reported. He had precedent and concurrent bacterial infections as most of these cases described. Low peripheral WBC and myeloblasts, Auer-rod positive blasts, bone marrow eosinophilia with atypical eosinophils, and a partial deletion of chromosome 16 were favorable prognostic parameters. A brief review of the literature and possible explanations for the regulation of granulopoiesis are presented.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Kinderdermatologie ; Exanthem ; Kinder ; Key words Pediatric dermatology ; Exanthema ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Unilateral laterothoracic exanthem a (ULE) is a self-limited, probably infectious-allergic skin disease predominately affecting small children. We describe five such cases. The typical unilaterally located or at least unilaterally dominant exanthem usually starts in the axillary region and is characterized by red, partly confluent papules and fine scales. Two of the children presented with atypical manifestations of ULE. Due to its asymptomatic course, therapy is not necessary in the majority of cases.
    Notes: Zusammenfassung 5 Kinder mit der Diagnose eines unilateralen laterothorakalen Exanthems (ULE) werden vorgestellt. Beim ULE handelt es sich um eine selbstlimitierende, vermutlich infektallergische Hauterkrankung, die hauptsächlich im Kleinkindesalter auftritt. Das typischerweise streng einseitig lokalisierte, immer jedoch einseitig dominierende Exanthem geht meist von der Axillarregion aus und zeigt erythematöse, teils konfluierende Papeln. Zwei der fünf Kinder zeigten auch atypische Hautveränderungen eines ULE. Eine Behandlung ist aufgrund seines überwiegend asymptomatischen Verlaufs in der Mehrzahl der Fälle nicht notwendig.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 51 (2000), S. 612-614 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Keratoakanthom ; Methotrexat ; Injektion ; Keywords Keratoacanthoma ; Methotrexate ; Intralesional injection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract A 53 year old female patient developed a keratoacanthoma, present on the left side of her nose for two months. After repeated unsuccessful trials with cryotherapy, she was treated with intralesional injection of methotrexate performed twice with a weekly internal. This led to complete resolution within 5 weeks. Although controlled studies on the effect of methotrexate in keratoacanthoma are not available, the rapid regression and the good cosmetic result suggest that this therapy may play a beneficial role in treating these lesions especially in problem locations.
    Notes: Zusammenfassung Eine 53 Jahre alte Patientin entwickelte über 2 Monate ein Keratoakanthom am linken Nasenflügel. Nach wiederholten erfolglosen kryotherapeutischen Behandlungsversuchen erfolgten zweimal im Abstand von 7 Tagen intraläsionale Methothrexat-Injektionen, wonach es innerhalb von 5 Wochen zu einer vollständigen Abheilung kam. Obwohl kontrollierte Studien über die Therapie von Keratoakanthomen mit Methotrexat bislang fehlen, legt die schnelle Tumorregression und das gute kosmetische Ergebnis diese Art der Therapie bei operationstechnisch schwierig lokalisierten Tumoren nahe.
    Type of Medium: Electronic Resource
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