ISSN:
1435-1463
Keywords:
Keywords: Cerebrospinal fluid
;
β-endorphin
;
substance P
;
age.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary. To evaluate the early age-related changes in neuropeptides, we have measured the cerebrospinal fluid (CSF) levels of β-endorphin and substance P in young patients over a range of ages. Specimens of CSF were obtained from 39 neurologically normal children, aged 1 month to 10 years of age, and in 9 adult controls. CSF levels of both neuropeptides were observed to peak during the first year of life, and showed a negative correlation with increasing age. A significant positive correlation was observed between the CSF level of β-endorphin and that of substance P.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007020050037
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