ISSN:
0021-9541
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Long-term lymphoid cell lines (LTL) cultured under normal conditions use methionine primarily for protein synthesis, although a significant proportion is converted to S-adenosylmethionine (SAM) and used for synthesis of the polyamines, spermidine, and spermine. When LTL are cultured under conditions of high cell density, there is an initial phase of rapid protein synthesis and accumulation of SAM as found under normal culture conditions, but this soon ceases. Polyamine synthesis is small under these conditions, despite the presence of relatively large amounts of SAM.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jcp.1041060306
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