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  • Mass screening  (1)
  • PPPD with vessel  (1)
  • 1
    ISSN: 1436-0691
    Keywords: Pylorus-preserving ; pancreatoduodenectomy ; PPPD with vessel ; preservation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Classical pancreaticoduodenectomy for malignant tumors of the pancreatoduodenal region or chronic pancreatitis has recently been discussed in terms of the quality of life, associated with long-term postoperative morbidity. Pylorus-preserving pancreatoduodenectomy (PPPD) for the patient with chronic pancreatitis was first reported by Traverso and Longmire. Since that time, PPPD has become an accepted surgical procedure that is being increasingly indicated for certain malignancies. Herein, we report a PPPD that also preserves the parapancreatoduodenal vessels. The reasons why PPPD with the preservation of these vessels is significant are related to the length of the preserved duodenum and the reactions of gastrointestinal hormones. However, it may appear that this new PPPD poses a little greater risk of cancer recurrence, since the surgery is less radical than the usual PD. If the indications listed below are strictly observed, this operation should enable. The indications are: (1) chronic pancreatitis with tumor formation in the pancreatic head, (2) ampullary carcinoma, (3) inferion biliary duct carcinoma, (4) early duodenal carcinoma (all without pancreatic invasion), and (5) certain benign cystic tumors. Whether this operation should also be recommended for patients with small carcinomas or islet cell tumors arising in the head of the pancreas is now being investigated.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1076
    Keywords: Neuroblastoma ; Mass screening ; Vanillylmandelic acid ; Homovanillic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fluctuations in the amount of vanillylmandelic acid (VMA) and homovanillic acid (HVA) were studied in random urine samples from 13 infants with neuroblastoma. In patients with a small tumour, many samples contained amounts below the cut off values, suggesting that detection of a patient with neuroblastoma depended on mathematical probability. Using high performance liquid chromatography a patient with a tumour of about 10 g may well be overlooked, whereas a patient whose tumour weighs over 30 g would probably be detected. With qualitative screening, although more likely to miss a patient with low VMA excretion, a patient with a tumour weighing over 50 g would be detected. In a thorough hospital examination care should be exercised in interpreting borderline values of VMA and HVA; excretion information suggesting the existence of a tumour may aid localization by radiological imaging procedures.
    Type of Medium: Electronic Resource
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