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  • 1
    Electronic Resource
    Electronic Resource
    An experimental study of mucociliary pathology of the eustachian tube in otitis media with effusion induced by irradiation (1989)
    Springer
    European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 428-432 
    Details
    ISSN: 1434-4726
    Keywords: Otitis media with effusion ; Mucociliary system ; Eustachian tube ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have examined the function and fine structure of the mucociliary system of the eustachian tube in an experimental study of otitis media with effusion induced by X-ray irradiation. Functional examination demonstrated that the ciliary activity was diminished in such a condition, while morphological observations showed pathological findings including compound cilia, vacuolation of ciliated cells and expansion of intercellular space. These findings show that irradiation-induced otitis media with effusion results in impairment of the mucociliary system. As evidenced by these studies, the mucociliary system in the eustachian tube has an important role in the clearance of fluid produced in the tympanic cavity as well as affording improvement in this disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00464303
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Abnormal mucociliary function in a mucocoele of the maxillary antrum (1986)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 207-210 
    Details
    ISSN: 1434-4726
    Keywords: Maxillary sinus mucocoele ; Mucociliary system ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have examined the mucociliary function present in a mucocoele of the maxillary antrum and have found certain abnormalities in the tissues studied. Our findings also indicate that the mucocoele's intrinsic pathology is too complex to be improved by any conservative treatment and justifies its surgical removal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00470623
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of human middle ear effusions on the mucociliary system of the tubotympanum in the guinea pig (1995)
    Springer
    European archives of oto-rhino-laryngology and head & neck 252 (1995), S. 35-41 
    Details
    ISSN: 1434-4726
    Keywords: Otitis media with effusion Tubotympanum ; Mucociliary system ; Guinea pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effusion fluid resulting from otitis media contains a variety of inflammatory substances. This middle ear effusion (MEE) may be itself affect the mucosa of the tubotympanum and contribute to chronicity of the condition. The present study was designed to elucidate in vitro and in vivo effects of MEEs on the mucosa of the guinea pig tubotympanum. The results obtained demonstrated that the ciliary activity of the eustachian tube was reduced in the presence of human MEEs. This activity decreased to approximately 80% in the presence of serous MEE at 48 h and was 60% after exposure to mucoid MEE. Intratympanic inoculation of human MEEs resulted in accumulation of a serous effusion in the tympanic cavity. Histologic study of the tubotympanum in inoculated animals demonstrated mucociliary dysfunction as well as a general inflammatory process and increased vascular permeability. This damage was more prominent following inoculation with the mucoid MEEs. The ciliary depression and inflammation found in the tubotympanum suggest that the pathologic nature of MEEs may be, at least partially, responsible for the chronicity of otitis media.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00171438
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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