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Myelin changes in leprous neuropathy (1987)

Jacobs, J. M. ; Shetty, V. P. ; Antia, N. H.

Springer

Acta neuropathologica 74 (1987), S. 75-80

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ISSN: 1432-0533

Keywords: Leprosy neuropathy ; Peripheral nerve ; Myelin ; Myelin periodicity ; Artefact

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Myelin changes were observed in fibres of nerves from cases of leprosy. The myelin had a ‘loosened’ appearance caused by increased and irregular separation of the intraperiod line. ‘Loosening’ might affect all, or only some, of the lamellae forming a myelin sheath. There was a pathcy distribution of fibres with abnormal myelin, and they were seen only in nerves showing other marked pathological changes including the presence of oedema. The appearances are suggestive of intramyelinic oedema which may be related to the presence of endoneurial oedema.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00688341

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