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  • 1
    Digitale Medien
    Digitale Medien
    Dysmyelination in Chow Chow dogs: Further studies in older dogs (1981)
    Springer
    Acta neuropathologica 55 (1981), S. 81-87 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Canine CNS ; Myelination ; Hypomyelinogenesis ; Electron microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The ultrastructure of myelin deficiency in Chow Chow dogs was studied in the spinal cord of a 15-month-old and a 3-year-old animal. It was found that myelination progresses with age in these dogs but is still deficient at the age of 3 years. The findings included axons with thin or uncompacted myelin sheaths, separated from each other by massive astrocytosis, and bizarre myelin formations. Normal numbers of morphologically normal oligodendrocytes were present in the myelin-deficient areas. The disease in these Chow Chow dogs consists of a strongly retarded myelination which is possibly due to a dysfunction or delay in glial maturation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00699232
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Dysmyelination of the central nervous system in the Chow-Chow dog (1978)
    Springer
    Acta neuropathologica 42 (1978), S. 211-215 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Canine CNS ; Myelination ; Hypomyelinogenesis ; Electron microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Five Chow-Chow dogs from three different litters had generalized body tremors since birth. Histologically a severe myelin deficiency was found in the central nervous system. The peripheral nerves were normally myelinated. Electron microscopically abnormally thin myelin sheaths and completely naked nerve fibers were found. There were many astrocytes in the myelin deficient areas as well as cells with the characteristic features of oligodendrocytes but also containing fibrils. The present cases are compared to other dysmyelinating diseases and possible pathogenetic mechanisms are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00690359
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
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