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Edwards, A. V. ; Ghatei, M. A. ; Bloom, S. R.

Springer

Cellular and molecular life sciences 50 (1994), S. 725-726

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ISSN: 1420-9071

Keywords: Nitric oxide ; insulin ; endocrine pancreas ; L-NAME

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract Mean plasma insulin concentration was reduced and mean plasma glucose concentration increased following the administration of N-nitro-L-arginine methyl ester (L-NAME; 100 μmol kg−1 i.a.) in conscious calves given continuous infusions of exogenous glucose (30–60 μmol min−1 kg−1 i.v.). It is concluded that the rise in plasma insulin concentration which occurs in these animals in response to glucose is mediated, at least in part, by a nitric oxide-related factor (NOx).

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01919371

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