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Neuropathological changes of the nucleus accumbens in Huntington's chorea (1981)

Bots, G. Th. A. M. ; Bruyn, G. W.

Springer

Acta neuropathologica 55 (1981), S. 21-22

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ISSN: 1432-0533

Keywords: Huntington's chorea ; Nucleus accumbens ; Nuclear membrane indentation

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Ultrastructural analysis of the ncl. accumbens, frontal cortex, and caudate nucleus of ten patients with Huntington's chorea revealed nuclear membrane indentation of remaining neuronal elements in 〉25%, 〈5%, and 〈2%, respectively. This phenomenon was not observed in ten non-choreic control brains obtained from patients with Alzheimer's disease, Parkinson's disease, and non-demented elderly people. The pathogenetic mechanisms leading to this phenomenon are discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00691525

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