ISSN:
1432-1041
Keywords:
Oxprenolol
;
airways obstruction
;
beta-2 blockade
;
statistical methods
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary In a double blind trial in 11 control subjects and 12 bronchitic patients against an inert control oxprenolol produced significant worsening in airways obstruction in 6 control and in 7 patients. There was marked individual variation in response and no way was found to predict the susceptible subjects. Objective measurement of indices of airways obstruction and the effect of oxprenolol on them is essential where there is significant respiratory impairment. Great care must continue to be exercised since a significant proportion of bronchitic patients will be adversely affected by this drug.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00561658
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