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  • 1
    Electronic Resource
    Electronic Resource
    Intraperitoneal hypercoagulation and hypofibrinolysis is present in childhood peritonitis (1999)
    Springer
    Pediatric nephrology 13 (1999), S. 284-287 
    Details
    ISSN: 1432-198X
    Keywords: Key words Fibrinolysis ; Peritonitis ; Peritoneal dialysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  An increased rate of obstruction of peritoneal dialysis catheters is observed during peritonitis. Hypercoagulation and hypofibrinolysis may explain this increased occurrence. We studied plasminogen activator inhibitor type 1 antigen (PAI-1), tissue-type plasminogen activator antigen (t-PA), D-dimer (DD), plasmin-α2-antiplasmin complexes (PAP), and thrombin-antithrombin III complexes (TAT) in 7 children with peritonitis (group A) and 12 children during stable peritoneal dialysis (group B). Albumin, β2-microglobulin, IgG, and α2-macroglobulin were measured for baseline transperitoneal protein transport. After a dwell of 6 h with 1.36% Dianeal, dialysate and serum samples were collected. Dialysate to plasma ratios of all proteins were calculated. During peritonitis (group A) TAT was higher: 34.7 versus 22.0 (P=0.01). PAI-1 was increased in group A: 76.5 versus 22.9 (P=0.004). PAP was decreased during peritonitis (group A): 24.9 versus 39.3 (P=0.01). In group A, DD were decreased. 10.8 versus 26.7 (P=0.002). t-PA was similar in both groups (23.7 in group A vs. 27.7 in group B; P=0.26). In both groups TAT, PAI-1, t-PA, PAP, and DD were significantly higher than in baseline transperitoneal transport, suggesting intraperitoneal production. Hypercoagulability and hypofibrinolysis were present during peritonitis compared with the control situation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050609
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Infectious and surgical complications of childhood continuous ambulatory peritoneal dialysis (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 377-380 
    Details
    ISSN: 1432-1076
    Keywords: Continuous ambulatory peritoneal dialysis ; Surgical complications ; Peritonitis ; Hernias ; Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 10-year retrospective study was performed with respect to the incidence of infectious and surgical complications in a young paediatric continuous ambulatory peritoneal dialysis population of 43 children (mean age 4.5 years [range 2.5 months-15.8 years]). The incidence of infectious complications such as peritonitis and catheter-related infections correlated well with the results of other studies. A relatively high incidence of hernias (53%) was seen in our population, probably caused by the lower mean age of the children. Obstructions were caused by omental wrapping, peritonitis, or operative procedures and did not correlate with the period of cathter function. Early leakage occurred within 5 days after catheter implantation. Later leakages were preceeded by another complication, such as infection or obstruction. In early leakage, in contrast to later leakage, the catheter could be maintained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113262
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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