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  • Phanerochaete chrysosporium  (1)
  • continuous sterilization  (1)
  • 1
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 41 (1993), S. 900-913 
    ISSN: 0006-3592
    Schlagwort(e): sterilization, sterilizer ; continuous sterilization ; fermentation medium ; particle ; solids ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: An improved mathematical model was developed to design a continuous sterilizer for liquid fermentation media containing suspended solids. Unsteady-state energy balances were used to determine the temperature distribution in the liquid medium and in the solid particles as a function of time and position within the particle, as the medium flows through the sterilizer. Such temperature profiles were used to determine the level of microbial reduction achieved by each component of the sterilizer and by the entire sterilization process. A considerable difference exists between the temperature in the particle core and in the surrounding liquid. This has a significant impact on the degree of sterility achieved by the process. The level of microbial reduction in the particles was found to be tens and or even hundreds of order of magnitude lower than the corresponding level achieved in the liquid. The role of the particle material on the degree of sterilization was also investigated. Solid materials typically found in fermentation media, such as wood or flour clumps were found to offer considerable resistance to the sterilization of the organisms lodged inside them. © 1993 Wiley & Sons, Inc.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 46 (1995), S. 599-609 
    ISSN: 0006-3592
    Schlagwort(e): Phanerochaete chrysosporium ; white rot fungus ; chlorophenol ; optimization ; modeling ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The biodegradation of 2,4,6-trichlorophenol and 2,4,5-trichlorophenol by the white rot fungus Phanerochaete chrysosporium was studied in batch and continuous reactor systems. Experiments were conducted in shake flasks as well as in packed-bed reactors in which the fungus was immobilized. The degradation rates in the packed-bed reactors were found to be two orders of magnitude greater than those obtained in the shake flasks in which the fungus was just suspended. The degradation rate was found to be influenced by the concentrations of the carbon and nitrogen sources, pH, and fluid shear stress. Optimal ranges of these parameters to maximize biodegradation were determined. A mathematical model was developed in which the degradation process was assumed to consist of two sequential reaction steps, the first catalyzed by an extracellular enzyme system and the second requiring the presence of the mycelium. The deactivation of the extracellular enzyme system was also accounted for in the model. The Michaelis-Menten and the enzyme deactivation parameters were determined independently. Good agreement between the experimental data and the results produced by the regression was found. © 1995 John Wiley & Sons, Inc.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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