ISSN:
0894-3230
Schlagwort(e):
Organic Chemistry
;
Physical Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
,
Physik
Notizen:
Using a series of equations connecting experimental and theoretical values, it is possible to discuss the origin of the N-methylation effect in azoles dissolved in water and dimethyl sulphoxide. The existence in the azoles studied of a linear relationship between the gas → solution transfer enthalpies and the charge on the pyrrole hydrogen atom demonstrated the fundamental importance of the loss of an active centre for solvation. For the imidazole-N-methylimidazole pair, the complete thermochemical cycle has been determined, allowing the apparent lack of an effect of N-methylation on the basicity in solution to be discussed.
Zusätzliches Material:
2 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/poc.610020807
Permalink