ISSN:
1573-8221
Keywords:
Progesterone
;
progesterone receptor
;
progesterone analog
;
steroid-receptor interaction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Binding of3H-16α, 17α-cyclopropanoprogesterone (CPG) and3H-progesterone (PG) to progesterone receptors in soluble fraction of rat uterus is studied. It is shown that CPG and PG specifically bind to the protein with similar affinity and binding capacity. Unlabeled PG competitively inhibits the binding of CPG, and unlabeled CPG competitively inhibits the binding of PF with the same efficiency. Dissociation of CPG- and PG-receptor complexes is characterized by the same dissociation constant.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02445287
Permalink