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  • 1
    Electronic Resource
    Electronic Resource
    Preoperative and postoperative CA-125 serum levels in primary Fallopian tube carcinoma (1994)
    Springer
    Archives of gynecology and obstetrics 255 (1994), S. 65-68 
    Details
    ISSN: 1432-0711
    Keywords: Fallopian tube carcinoma ; CA-125 serum levels ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Levels of CA-125 were determined pre- and postoperatively in 13 patients with Fallopian tube cancer. Values before surgery were significantly higher (Median 1220 IU/ml, 90–5000 IU/ml) compared with postoperative levels (Median 194 IU/ml, 67–880 IU/ml) (P=0.0052). Correlation analysis with FIGO stage and grading failed to show any statistical significance, but a trend for a positive correlation with FIGO stage and preoperative values could be observed. The CA-125 antigen is expressed by Fallopian tube carcinoma and should therefore be used in diagnosis and follow-up.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02391799
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prognostic significance of steroid hormone receptors and histopathological characterization of human breast cancer (1987)
    Springer
    Journal of cancer research and clinical oncology 113 (1987), S. 285-290 
    Details
    ISSN: 1432-1335
    Keywords: Breast cancer ; Steroid hormone receptors ; Histopathology ; Tumor differentiation ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Since breast cancer is a heterogeneous disease, evaluation of prognosis is an obvious problem. The prognostic significance of several pathological criteria including tumor grading according to WHO, steroid hormone receptor status, histological tumor type, tumor size, and axillary lymph node involvement have been investigated. The single parameters with the strongest prognostic significance were axillary lymph node status, tumor grading, and estrogen receptor status. A significant direct correlation exists between tumor grading and steroid hormone receptors, but nevertheless on stratified analysis both factors independently affected the risk of death. Tumor size had weak prognostic importance and histological tumor types failed to show any statistically significant differences with regard to survival.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00396387
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Thymidine labeling index and Ki-67 growth fraction in breast cancer: Comparison and correlation with prognosis (1994)
    Springer
    Breast cancer research and treatment 32 (1994), S. 165-175 
    Details
    ISSN: 1573-7217
    Keywords: breast cancer ; prognosis ; growth fraction ; Ki-67 ; TLI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In situ determination of proliferative activity was performed on 184 consecutive primary invasive breast cancers. Methods used were monoclonal antibody Ki-67 in immunohistochemistry and thymidine labeling index. Tumor proliferation correlated between both methods (p = 0.0001). For thymidine labeling index and Ki-67, respectively, significant correlations existed with histologic tumour grade and steroid hormone receptors (Tumor grade: TLIp = 0.0001; Ki-67 p = 0.0001. ER-ICA: TLI = 0.0001; Ki-67 p = 0.014. PgR-ICA: TLIp = 0.0001; Ki-67 p = 0.0008). For thymidine labeling index a significant correlation was demonstrated for overall survival (p = 0.001) and recurrence free survival (p = 0.01). No statistical significance was observed for clinical outcome and Ki-67 (overall survival p = 0.18; recurrence free survival p = 0.1). None of the factors, TLI or Ki-67, was an independent prognostic factor as demonstrated by multivariate analysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00665767
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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