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  • Quality criteria  (1)
  • Seed germination  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Proteolysis in the axis of the germinating pea seed (1979)
    Springer
    Planta 147 (1979), S. 111-116 
    Details
    ISSN: 1432-2048
    Keywords: Aminopeptidase ; Axis ; Carboxypeptidase ; Endopeptidase ; Pisum ; Seed germination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Autoproteolytic, caseolytic and haemoglobin degrading activities, carboxypeptidase and aminopeptidase activities have all been measured in extracts prepared from the radicle of germinating pea seeds (Pisum sativum L.). With increasing time from the beginning of imbibition, the spectrum of protein degrading enzyme activities changed in a complex manner. As a proportion of total autoproteolytic activity, acid proteinases declined, while sulphydryl-and serine-active site endopeptidases accounted for increased proportions of the total activity. The distribution of protein degrading enzyme activities in the root tip compared with the balance of the root was determined after 4 days, at the onset of cell division in the root apex. On a fresh weight basis the tip was enriched ca. 2-fold in protein concentration and all of the exopeptidases. Autoproteolytic activity was concentrated in the tip to a lesser degree, and haemoglobin degrading activity not at all. In contrast, the root tip was depleted in caseolytic activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00389509
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  • 2
    Electronic Resource
    Electronic Resource
    PET radiopharmaceuticals in Europe: Current use and data relevant for the formulation of summaries of product characteristics (SPCs) (1995)
    Springer
    European journal of nuclear medicine 22 (1995), S. 1420-1432 
    Details
    ISSN: 1619-7089
    Keywords: Positron emission tomography ; PET ; Radiopharmaceuticals ; Quality criteria ; Toxicology ; Dosimetry ; Survey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The increasing use of radiopharmaceuticals for positron emission tomography (PET) has come to the attention of regulatory bodies. In order to help authorities in all aspects, the EANM has formed a task group for licensing PET radiopharmaceuticals; this group has surveyed the use of these compounds in Europe by a questionnaire. The number of PET centres that responded to the questionnaire was 26, which included more than 90% of the larger European PET centres. The survey showed that 2-[18F]fluoro-2-deoxyglucose is by far the most important PET radiopharmaceutical with more than 200 applications per week, followed by [15O]water, [15O]carbonmonoxide, [13N]ammonia, [11C]-l-methionine, andl-6-[18F]fluoro-DOPA. More than 25 other PET radiopharmaceuticals are in regular use, however, at rather low application frequencies. The data were used by the European Pharmacopoeia Commission for its priority rating for requesting the formulation of monographs. Since it is likely that group registrations will be issued by authorities for the PET radiopharmaceuticals, relevant data on toxicity and dosimetry for the formulation of summaries of product characteristics have been collected by the task group as well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01791152
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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