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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 151 (1977), S. 201-218 
    ISSN: 1432-0568
    Keywords: Cerebellum ; Albino rat ; Ontogeny ; Quantitative anatomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The quantitative postnatal changes of the cerebella of 65 Wistar rats aged 2–120 days have been examined. The cerebellar volume increases in two phases: The first phase lasts from birth to the seventh postnatal week. The second phase begins ten weeks post partum and lasts for a longer period than the first phase. The cerebellar surface increases continuously from birth to the end of the seventh week. The volume of the external granular layer is maximal when the organ grows rapidly. The external granular layer has nearly disappeared 24 days after birth; the volume of the internal granular layer is maximal at this time. Later on, the volume and the width of the internal granular layer decrease. Myelinization of the cerebellar fibers and growth of the molecular layer run parallel to this decrease. The second late, but protracted growth of the cerebellum, ten weeks after birth, is due to an increase of the molecular and medullary layer. These findigns are in good accord with histological, histochemical, and ultrastructural observations of other authors.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 168 (1983), S. 101-116 
    ISSN: 1432-0568
    Keywords: Capillaries ; Blood-brain barrier ; Quantitative anatomy ; Cerebellar cortex ; Senile rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ultrastructural changes including reduced electron density, reduction in polysomes and cisternae of rough endoplasmic reticulum occur in the cytoplasm of endothelial cells and pericytes in the cerebellar cortex of senile virgin female Han: WIST-rats in comparison to 3-month old virgin rats. Processes of pericytes cover less of the capillary surface in the cerebellar cortex of senile rats; moreover, arithmetic and harmonic mean thickness of the endothelium and relative volume of mitochondria in endothelial cells and pericytes are reduced, whereas the luminal diameter of the capillaries, harmonic and arithmetic mean thickness of pericytes and their processes and of the basal laminae between endothelial cells and astrocytes (abbreviated BAL 1), pericytes and astrocytes (BAL 2) and endothelial cells and pericytes (BAL 3) increase. The increase in harmonic mean thickness of the basal laminae is statistically significant (α≦0.05) and compensates for a decrease in thickness of capillary endothelium. Consequently, the total barrier mass and thickness of cerebellar cortical capillaries in senile animals is higher than in young individuals.
    Type of Medium: Electronic Resource
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