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  • 1
    ISSN: 1432-0428
    Keywords: Keywords Perimetry ; Visual Field ; Short-Wavelength Sensitivity ; Selective Loss ; Diabetic Macular Oedema.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of the study was to compare the sensitivity of short-wavelength and conventional automated static threshold perimetry for the psychophysical detection of abnormality in patients with clinically significant diabetic macular oedema. The sample comprised 24 patients with clinically significant diabetic macular oedema (mean age 59.75 years, range 45–75 years). One eye of each patient was selected. Exclusion criteria included the presence of lenticular opacity. The sensitivity of the macular visual field of each patient was determined with programme 10–2 of the Humphrey Field Analyser on two occasions, using both short-wavelength and conventional stimulus parameters; the results of the second session were analysed to minimise learning effects. A pointwise horizontal hemifield asymmetry analysis was derived for short-wavelength perimetry (thereby negating the influence of pre-receptoral absorption); the pointwise pattern deviation probability plot was analysed for conventional perimetry. Abnormality was defined as 3 or more contiguous stimulus locations with negative asymmetries (short-wavelength) or reduced sensitivity values (conventional) that resulted in a statistical probability level of p less than 0.05. The fields of 8 patients were abnormal as assessed by conventional perimetry while all were classified as abnormal using short-wavelength perimetry. In the 8 patients who exhibited both abnormal conventional and abnormal short-wavelength perimetry results, the extent of field loss was generally greater using short-wavelength perimetry. The position of the localised field loss (i. e. as distinct from field loss that was generalised across the visual field) assessed by short-wavelength perimetry corresponded with the clinical mapping of the area of diabetic macular oedema but the extent of this loss was generally greater than that suggested by clinical assessment. Short-wavelength automated perimetry offers improved sensitivity for the psychophysical detection of clinically significant diabetic macular oedema. [Diabetologia (1998) 41: 918–928]
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 62 (1986), S. 97-105 
    ISSN: 1573-2622
    Keywords: half-field stimulation ; source derivation ; visually evoked potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There has been much recent conjecture over the apparent source location of the visually evoked potential, particularly in considering the lateralization found in half-field pattern reversal stimulation. This paper presents an alternative by directly identifying the sinks or sources present in the scalp current flow as these correspond to the maximal current flow into or out of the cortex (Nunez, 1981). Hjorth (1975) introduced a practical procedure for source derivation which has proved useful in the interpretation of the electroencephalogram (Wallin and Stalberg, 1980). We have applied source derivaton to cortical evoked potentials and present results obtained from right and left half-field stimulation, (Clement, Flanagan and Harding, 1985) and upper and lower field stimulation in normal subjects and patients with visual deficits.
    Type of Medium: Electronic Resource
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