ISSN:
1573-1561
Keywords:
Sex pheromone
;
drugstore beetle
;
Coleoptera
;
Anobiidae
;
Stegobium paniceum L.
;
stegobinone
;
diastereoisomer inhibition
;
pheromonal activity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Stegobinone, (2S, 3R, 1′R)-2,3,-dihy dro-2,3,5-trimethyl-6-(1′-methyl-2′-oxobutyl)-4H-pyran-4-one, the sex pheromone of drugstore beetles (Stegobium paniceum L.), elicited the pheromonal response from the males of the species in our bioassay system; however, the synthesized diastereomeric mixture of this compound was actually inactive to the males. Although the stegobinone isolated from the beetles of this species had significant activity, its enantiomeric [(±)-2S,3R,1′S-] and diatereomeric [(±)-2S,3S,1′RS-] isomers were inactive. Adding the (±)-2S,3R,1′S isomer to stegobinone significantly reduced the male response. Furthermore, the activity of Stegobinone vanished on keeping it at room temperature for two weeks. In such a stored stegobinone sample, the presence of 2S,3R,1′S isomer, the inhibitory component, was confirmed. This isomer might be produced by C-1′ epimerization during storage.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01013235
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