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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 54 (1976), S. 449-450 
    ISSN: 1432-1440
    Keywords: Template activity of Chromatin ; RNA-Polymerase III rat liver ; Development ; Chromatin-Matrizenaktivität ; RNA-Polymerase III ; Rattenleber ; Entwicklung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Matrizenaktivität von Chromatin aus gereinigten Rattenleberzellkernen ist in der Fetalzeit niedrig, erreicht ihr Maximum um den 1. Lebenstag und steigt nach einem vorübergehenden Absinken vom 10.–40. Lebenstag allmählich auf Erwachsenenwerte an. Dieser Befund läßt sich mit entwicklungsspezifischen Aktivitätsveränderungen der DNA-abhängigen RNA-Polymerase III im Cytoplasma der Leberzelle gut korrelieren.
    Notes: Summary The template-activity of chromatin isolated from liver nuclei of developing rats increases sharply at birth and decreases remarkable until the 10th day. Between the 10th and the 40th day a slow increase was shown in template activity of chromatin tested with purified E.-coli RNA-polymerase (EC 2.7.7.6). We correlated these findings with changes of RNA-polymerase III-activity in rat liver during development.
    Type of Medium: Electronic Resource
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