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  • Temporal trends  (1)
  • pituitary adenoma  (1)
  • temporal ischemia  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 13 (1992), S. 507-510 
    ISSN: 1590-3478
    Keywords: Pure word deafness ; temporal ischemia ; SPECT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario La sordità verbale pura à una sindrome di non frequente riscontro, inquadrata tra le forme di afasia, caratterizzata da sordità completa e conservata possibilità di comprendere e leggere il messaggio scritto, senza turbe espressive dell'eloquio. In genere il quadro clinico si presente associato ad altri deficit neurologici focali importanti e molto raramente, come nella nostra esperienza, in forma isolata. Viene descritto il caso di un uomo di 61 anni, cardiopatico, che ha presentato una sordità verbale pura in seguito a due episodi, ravvicinati nel tempo, di ischemia cerebrale acuta. Il paziente è stato studiato con tecniche di neuroimaging: TAC, SPECT (non sono presenti in tal senso dati in letteratura), RMN; e neurofisiologiche: EEG, BAER, Stapedial reflex. Le conclusioni sono esaminate alla luce dei dati e dei lavori presenti in letteratura.
    Notes: Abstract Pure Word Deafness is a clinical syndrome included among the aphasias and is marked by complete deafness of sudden onset with conserved ability to understand and read the written word and with no speech disorders. We report the case of 61 year old man in whom pure word deafness developed after two episodes of acute cerebral ischemia in quick succession. Neuroimaging procedures, that is: computed tomography scan, single photon emission computed tomography and magnetic resonance imaging, revealed the presence of two ischemic lesions in the temporal cortex bilaterally. Neurophysiological investigations (electroencephalogram, brainstem auditory evoked potentials and stapedial reflex) were also studied. We discuss the outcome of all these investigations in the light of the relevant published work.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1590-3478
    Keywords: Fibrous dysplasia of bone ; pituitary adenoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Riportiamo il caso di un paziente di 18 anni affetto da una displasia fibrosa dell'osso con varie anomalie endocrine. Gli esami ormonali rivelarono alti livelli di prolattina, TSH e GH e bassi livelli di testosterone e LH. I test al TRH ed al GnRH mostrarono una normale risposta ipofisaria nonostante gli alti livelli basali di alcuni ormoni. I ritmi circadiani erano conservati. Gli esami neuroradiologici effettuati (TAC, stratigrafia della sella e cisternografia con metrizamide) non rivelarono alcun segno sicuro di adenoma ipofisario se non la probabile erosione del pavimento della sella segnalato dalla stratigrafia. I nostri dati sono in accordo con la presenza di un adenoma misto dell'ipofisi e di più adenomi. In conclusione segnaliamo l'importanza di un corretto studio neurologico e neuroendocrino della displasia fibrosa dell'osso particolarmente in quella a localizzazione cranica.
    Notes: Abstract An 18 year old man with fibrous dysplasia of bone and several endocrine abnormalities was investigated. Laboratory tests showed high levels of prolactin, TSH and GH and low levels of testosterone and LH. TRH and GnRH showed normal responsiveness of the pituitary in spite of the high hormonal levels. The circadian rhythms disclosed no abnormalities of hypothalamic control. The neuroradiological study revealed pathological tissue but no positive sign of a pituitary adenoma, although the sella turcica polytomograms did suggest erosion of the floor. Our data are compatible with the presence of a mixed adenoma or adenomas of the pituitary. We emphasize the importance of a correct study, including neuroradiological and neuroendocrine investigations, in patients with fibrous dysplasia of bone.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1590-3478
    Keywords: Key words Stroke ; Incidence ; Fatality rate ; Temporal trends
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this study was to evaluate temporal changes of stroke in an Italian community by comparing the present incidence rates with those reported in the same area for 1989. The two studies were conducted by the same research group and met almost all the criteria proposed for an “ideal” stroke incidence study. The annual incidence rate per 1000 inhabitants increased (p 〈 0.01) by 29% from 2.23 (95% CL, 1.96–2.50) in 1989 to 2.89 (95% CL, 2.58–3.20) in 1997. No statistically significant change was found when these rates were adjusted to the 1991 Italian population. The overall incidence rate was 2.40 (95% CL, 2.14–2.66) in 1989 and 2.65 (95% CL, 2.39–2.91) in 1997. The thirty-day case fatality rate declined dramatically (p 〈 0.001) from 31% (95% CL, 26– 36) to 20% (95% CL, 16–24) between 1989 and 1997. Ageing of the population and better identification of cases could explain the high incidence rate, whereas the decrease of fatality rate may be due to a general improvement in acute care and inclusion of milder cases.
    Type of Medium: Electronic Resource
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