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  • Treatment-resistant schizophrenia  (1)
  • thermal diffusivity  (1)
  • 1
    Electronic Resource
    Electronic Resource
    A prospective study of clozapine in treatment-resistant schizophrenic patients (1989)
    Springer
    Psychopharmacology 99 (1989), S. S68 
    Details
    ISSN: 1432-2072
    Keywords: Clozapine ; Treatment-resistant schizophrenia ; Quality of life
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Preliminary results of a non-blinded prospective study of the effect of clozapine on symptomatology and social function in 51 treatment-resistant schizophrenic patients are reported. The mean duration of treatment at the time of this report was 10.3±8.1 months, median 7.6 months. Overall, 3/51 patients (60.8%) showed at least a 20% decrease in total BPRS, a criterion of improvement in the study of Kane et al. (1988). Four of 51 (7.8%) had at least a 50% decrease in total BPRS. Improvements in both positive and negative symptoms were noted. Marked improvements in social function were noted within the first 6 months of treatment. Improvement was first noted at all time points, with only 45.2% of improvers being identified after 6 weeks of treatment. These results suggest a 6–12-month trial may be desirable before deciding to discontinue clozapine because of insufficient response. Higher total Brief Psychiatric Rating Scale (BPRS) score and higher ratings on the Paranoid Disturbance subscales of the BPRS were factors which discriminated clozapine responders from non-responders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442563
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  • 2
    Electronic Resource
    Electronic Resource
    Thermal Diffusivity Measurement of Two-Layer Optical Thin-Film Systems Using Photoacoustic Effect1 (2000)
    Springer
    International journal of thermophysics 21 (2000), S. 543-552 
    Details
    ISSN: 1572-9567
    Keywords: antireflection coating ; parameter estimation ; photoacoustic effect ; thermal diffusivity ; through-plane
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this study, we designed and developed two-layer antireflection (AR) optical coating samples on glass substrates, using different evaporation conditions of coating rates and substrate temperatures for two dielectric materials, MgF2 and ZnS, with different refractive indices. The through-plane thermal diffusivity of these systems was measured using the photoacoustic effect. The optical thicknesses of MgF2 and ZnS layers were fixed at 5λ/4 (λ=514.5 nm) and λ, respectively, and the thermal diffusivities of the samples were obtained from the measured amplitude of the photoacoustic signals by changing the chopping frequency of the Ar+ laser beam. The results demonstrated that the thermal diffusivity of the sample fabricated under the conditions of 10μÅ·s−1 and 150°C had the maximum value and that the results were directly related to the microstructure of the film system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006612403028
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    Paper (German National Licenses)
    Fulltext
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