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  • 1
    Digitale Medien
    Digitale Medien
    Comparison of bleomycin and peplomycin toxicity on clonogenic tumor cells from various human tumors (1986)
    Springer
    Journal of cancer research and clinical oncology 112 (1986), S. 165-169 
    Details
    ISSN: 1432-1335
    Schlagwort(e): Bleomycin ; Peplomycin ; Tumor colony forming assay
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The cytotoxic effect of bleomycin and peplomycin was compared using a methylcellulose monolayer assay for the cultivation of human tumor cells. In 3 out of 4 samples from human malignant melanomas peplomycin proved to be more cytotoxic than bleomycin. Peplomycin was more cytotoxic than bleomycin in 1 of 5 myosarcoma samples, whereas 2 samples from squamous cell carcinomas of the lung showed identical dose response curves. In 1 carcinoma of the gall bladder peplomycin was more toxic than bleomycin.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00404401
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Tumor colony formation from human spontaneous tumors in a methylcellulose monolayer system (1984)
    Springer
    Research in experimental medicine 184 (1984), S. 137-143 
    Details
    ISSN: 1433-8580
    Schlagwort(e): Tumor colony forming assay ; Methylcellulose
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A methylcellulose monolayer system is described that facilitates the “in vitro” cultures of human spontaneous tumor cells. The tumor samples were disaggregated mechanically and cultured in 0.9% methylcellulose with 30% fetal calf serum in Iscove's modified Dulbecco's medium. Eighty-five individual tumor samples with different histological types were seeded, 45 gave rise to tumor cell colonies. The plating efficiency ranged from 0.02% to 0.22%. Cytologic and cytochemical staining from aspirated cells revealed the same morphology of cells as the cells in the suspension. A flattening of colonies, as it has been described by others using methylcellulose monolayer, was not observed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01852387
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
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