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Digitale Medien

Intermediate filament expression in prostate cancer (1996)

Nagle, Ray B.

Springer

Cancer and metastasis reviews 15 (1996), S. 473-482

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ISSN: 1573-7233

Schlagwort(e): prostate ; carcinoma ; intermediate filaments ; cytokeratin ; vimentin ; cytoskeleton

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary The human prostate is composed of a series of tubular-alveolar glands and their ducts surrounded by a fibromuscular stroma. The parenchymal glands secrete the seminal fluid and are anatomically arranged into the central, peripheral, and transitional zones. In this chapter the pattern of intermediate filament expression by the various epithelial components of the ducts, tubuloalveolar glands, and stroma are described. The changes which occur during malignant transformation from normal glands to prostatic intraepithelial neoplasia and subsequent invasive carcinoma are presented. The usefulness of cytokeratin markers in the diagnosis of prostate carcinoma is also discussed.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00054013

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