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  • electrophoretic variation  (2)
  • growth and reproduction complex  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Electrophoretic variation in low molecular weight lens crystallins from inbred strains of rats (1985)
    Springer
    Biochemical genetics 23 (1985), S. 787-800 
    Details
    ISSN: 1573-4927
    Keywords: electrophoretic variation ; lens crystallin ; rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Analysis of rat lens soluble proteins by analytical isoelectric focusing detected two inherited electrophoretic differences in low molecular weight (LM) crystallins from inbred strains of rats(Rattus norvegicus). The polymorphic lens crystallins were shown to be similar to a genetically variant LM crystallin, LEN-1, previously described in mice(Mus musculus) and encoded on chromosome 1, at a locus linked toPep-3 (dipeptidase). Linkage analysis demonstrated that the rat crystallin locus was loosely linked toPep-3 at a recombination distance of 38±4.5 U. These data suggest the conservation of a large chromosomal region during the evolution of Rodentia and support the hypothesis that the γ-crystallins are evolving more rapidly than α- or β-crystallins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00554088
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Electrophoretic variation in low molecular weight lens crystallins from inbred strains of rats (1985)
    Springer
    Biochemical genetics 23 (1985), S. 787-800 
    Details
    ISSN: 1573-4927
    Keywords: electrophoretic variation ; lens crystallin ; rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Analysis of rat lens soluble proteins by analytical isoelectric focusing detected two inherited electrophoretic differences in low molecular weight (LM) crystallins from inbred strains of rats(Rattus norvegicus). The polymorphic lens crystallins were shown to be similar to a genetically variant LM crystallin, LEN-1, previously described in mice(Mus musculus) and encoded on chromosome 1, at a locus linked toPep-3 (dipeptidase). Linkage analysis demonstrated that the rat crystallin locus was loosely linked toPep-3 at a recombination distance of 38±4.5 U. These data suggest the conservation of a large chromosomal region during the evolution of Rodentia and support the hypothesis that the γ-crystallins are evolving more rapidly than α- or β-crystallins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02399409
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Histopathology and cell culture characteristics of liver cells from grc − and grc + rats given diethylnitrosamine (1990)
    Springer
    Cell biology and toxicology 6 (1990), S. 205-217 
    Details
    ISSN: 1573-6822
    Keywords: chemical carcinogenesis ; genetics of cancer ; growth and reproduction complex ; MHC-linked genes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The histopathological response and cell culture characteristics of liver cells from the R16 (grc −) strain of rats, which carries an MHC-linked deletion, were examined one week after a single intraperitoneal injection of 200 mg/ kg body weight diethylnitrosamine (DEN) and were compared with the response of liver cells from wild type (grc+) rats. The DEN exposure induced hydropicl vacuolar changes in the parenchymal cells and a limited proliferation of oval cells in the periportal areas of the livers of both grc+ and grc rats. Primary culture of collagenase-digested livers consisted of parenchymal, bile ductular and oval-related cells as determined by cell-specific immunohistochemistry. Subpassaged cells from grc+ rats exhibited oval cell ultrastructural morphology, inducible histochemical staining for gammaglutamyl transpeptidase (GGT), and DEN-associated onset of anchorage-independent growth. Primary cultures of liver cells from R16 rats consistently failed to form cell strains upon subpassage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00249594
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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