Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Osseous metastases from a benign intraventricular meningioma (1992)
    Springer
    Acta neurochirurgica 117 (1992), S. 195-199 
    Details
    ISSN: 0942-0940
    Keywords: Antibodies ; monoclonal ; brain neoplasm ; meningioma ; neoplasm ; metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors report a case of a 6 month-old male presenting with increasing head circumference and a large benign intraventricular meningioma which was grossly removed at the initial surgery. Twenty-four months later, the patient returned with subcutaenous and osseous metastatic lesions at the site of the previous craniotomy, revealing the same histology as the original tumour. The presentation, pathology and management of this unique case are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400620
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Expression and release of interleukin-1 by human glioblastoma cells in vitro and in vivo (1993)
    Springer
    Acta neurochirurgica 121 (1993), S. 199-205 
    Details
    ISSN: 0942-0940
    Keywords: Brain ; glioblastoma ; interleukin-1 ; neoplasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study demonstrates interleukin-1 (IL-1) production by human glioblastorna cells bothin vitro andin vivo. The presence of IL-1α and IL-1β transcripts was analyzed in 4 cell lines. IL-1α mRNA was expressed constitutively in one cell line whereas constitutive IL-1β mRNA could not be detected in any of the cell lines. IL-1α transcripts could be induced with phorbol myristate acetate (PMA) or PMA plus lipopolysaccharide (LPS) in 2 of 4 cell Unes and IL-1β mRNA in 2 of 4 cell lines. Culture fluid from these cell lines was tested for the presence of IL-1 using a specific radioimmuno-assay for either IL-1α or IL-1β. In agreement with the results on RNA, one of 4 cell lines was found to constitutively produce IL-1α but not IL-1β. After treatment with PMA and LPS, IL-1α was detected in the culture fluid from two other lines and IL-1β in the medium from three lines. That the IL-1 produced by these cell lines was biologically active was confirmed in a two step thymocyte proliferation assay. IL-1 like activity was detected in all samples that were positive in the radio-immuno-assay. Finally, immunohistological analysis on fresh frozen tumour sections provided evidence for IL-1 production by glioblastoma cellsin vivo. Fourteen out of 28 glioblastomas were stained with an anti-IL-1α monoclonal antibody while none of them was stained with an anti-IL-1β antibody.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01809276
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...