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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Plant Science Letters 14 (1979), S. 185-192 
    ISSN: 0304-4211
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0378-1119
    Keywords: (Yeast ; gene regulation) ; transcription factor
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 101 (1981), S. 524-532 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Skeletal radiology 15 (1986), S. 372-375 
    ISSN: 1432-2161
    Keywords: Vertebral hemangioma ; Spinal cord compression ; Computerized tomography ; Myelography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two teenagers with spinal cord compression due to a thoracic vertebral hemangioma are presented. Myelography showed a complete block in both patients. Selective intercostal arteriography was normal or non-conclusive. Only computed tomography (CT) gave precise information about the extent and nature of the compressive lesion. In the first case it showed angiomatous involvement of the body and all parts of the neural arch of T4, and a posterior epidural ossified angiomatous mass. In the second case it showed angiomatous involvement of the vertebral body and an anterior extradural soft tissue mass; this latter was considered to represent a resolving extradural hematoma. CT, preferably performed after intrathecal contrast injection, is the diagnostic procedure of choice for spinal hemangioma with cord involvement.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 36 (1994), S. 134-136 
    ISSN: 1432-1920
    Keywords: Lumbar nerve root compression ; Sciatica ; Brown tumour ; Primary hyperparatyroidism ; Myelography ; Computed tomography (CT)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a unilateral intraspinal cyst-like lesion adjacent to the lamina and facet joint at the L4−L5 level producing sciatica. Histological examination revealed multinucleate giant cells suggesting a brown tumour. Further studies disclosed primary hyperparathyroidism, whose first manifestation was the lumbar nerve root compression. Previous cases of compression of neural structures by spinal brown tumours are reviewed and a radiological differential diagnosis is presented.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary There was no disturbance in the growth of Lemna minor L. with a SO2 concentration of up to 0.3 ppm in air. A SO2 concentration of 0.6 ppm caused an initial depression of the growth rate of about 25%, but in the course of adaptation, the rate rose to the values of the control. The average dry weight per frond was not influenced by the SO2 fumigation. The initial sporadic appearance of chloroses by fumigation with 0.6 ppm SO2 was considered a sign of the proximate toxicity limit for Lemna minor L. With 0.15 ppm SO2 in air, the size of the fronds was reduced. The average surface of the fronds was diminished by 0.3 ppm SO2 for about 16% as compared with the control plants. The protein remained quantitatively uneffected up to a SO2 concentration of 0.6 ppm. As a qualitative influence of SO2, the nitrogen content of the proteins remained constant, but the sulfur content of the proteins increased. Under 0.3 and 0.6 ppm SO2, the starch content decreased immediately by 20–30%, under 0.15 ppm SO2 the decrease reached the same level after a longer time than in the case of the higher concentrations. The SO2 concentrations up to 0.6 ppm had no effect on chlorophyll concentration. The contents of C, N, H, P, K, Na, Ca, Mg, Mn, and Fe were not effected by SO2 fumigation. Conclusion: SO2 may have some effects on product yield, even under low concentrations, without provoking acute damage; the plant is able to adapt by regulation of its metabolism, and enters a new steady state.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 117 (1992), S. 195-199 
    ISSN: 0942-0940
    Keywords: Antibodies ; monoclonal ; brain neoplasm ; meningioma ; neoplasm ; metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors report a case of a 6 month-old male presenting with increasing head circumference and a large benign intraventricular meningioma which was grossly removed at the initial surgery. Twenty-four months later, the patient returned with subcutaenous and osseous metastatic lesions at the site of the previous craniotomy, revealing the same histology as the original tumour. The presentation, pathology and management of this unique case are discussed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 118 (1992), S. 117-129 
    ISSN: 0942-0940
    Keywords: Extreme lateral lumbar disc herniation ; far lateral lumbar disc herniation ; foraminal disc herniation ; extraforaminal disc herniation ; intervertebral foramen ; lateral interpedicular compartment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The anatomy of the lateral aspect of the lumbar spine and our lateral microsurgical technique for extreme lateral lumbar disc herniations (ELLDH) is described. This study was based on the microdissection of 4 cadavers, on the morphometric evaluation of these as well as 6 dried cadaver spines and 8 lumbar CT scans, and on the use of this technique on over 200 cases. Level dependent changes in the posterior arch cause a shift of the disc space distally relative to the facet joint, an increasing amount of bone to overlie the intervertebral foramen, and a decreasing amount of working space within the exposure in the caudal direction. Therefore, more bone removal from the lateral aspect of the pars interarticularis and supero-lateral aspect of the facet joint is required in the lower lumbar spine. When the exposed ligamentum flavum is resected, the dorsal root ganglion is seen and access to the herniation and disc space is achieved. Level dependent changes in the pedicles and transverse processes lead to an alteration in the course and relationships of the nerves, thereby influencing the pathophysiology of and surgical technique for the ELLDH. The operative target is the lateral aspect of the pars interarticularis and not the intertransverse space as has been previously described. Our techniques allows for the early identification of the nerve with minimal risks of injury to it, to the adjacent vessels and to the structural integrity of the facet joint and pars interarticularis.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 127 (1994), S. 203-209 
    ISSN: 0942-0940
    Keywords: Extreme lateral lumbar disc herniation ; clinical characteristics ; lumbar spine ; incidence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective analysis of clinical characteristics of 178 consecutive patients with extreme lateral lumbar disk herniation, amongst 3047 patients operated on for herniated lumbar disc, is presented. The level specific incidence of extreme lateral disc herniation (ELLDH) ranged from a low of 4.5% at L 4–5 to peak of 17.4% at L 3–4 although the largest number of ELLDH occurred at L 4–5 and L5-S1 for a total number of 139 cases (78.1%). 43.6% of all L3 radiculopathies were caused by an L 3–4 ELLDH, whereas only 4.4% of all L 5 radiculopathies were caused by an L 5-S 1 ELLDH. Leg pain, either of the sciatic or the femoral type, was the first and dominant clinical symptom of radiculopathy, but pain radiation occurred not always in the appropriate dermatomal segment. ELLDH at upper levels (L 2–3 and L 3–4) caused usually none or only minor low back signs (76.2%), whereas ELLDH at lower levels more often caused moderate or major lumbar symptoms and signs (59.6%). Positive femoral nerve traction test with upper ELLDH showed a high frequency (84.4%) and reliability and is therefore an important clinical parameter in this situation. Motor deficits occurred more often (78.8%) than sensory deficits (46.6%), were usually of the monoradicular type and were therefore a more reliable clinical sign than sensory disturbances.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0942-0940
    Keywords: Boron neutron capture therapy ; BSH ; glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The disposition of Na2B12H11SH (BSH) in patients with malignant glioma has been investigated, in preparation for a Phase I clinical trial of boron neutron capture therapy. BSH was found to possess a linear disposition over the dosage interval investigated (up to 75 mg/kg). A bi-phasic blood pharmacokinetics was observed. Tumour-to-blood ratios showed variations between patients between 0.08 and 5.1. The data allow the definition of amount of BSH and timing of infusion for a Phase I clinical trial protocol.
    Type of Medium: Electronic Resource
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