ISSN:
1420-9071
Keywords:
Mitotic arrestants
;
spermatocyte
;
chromosomes
;
meiotic metaphase accumulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Three mitotic arrestants, colchicine, Colcemid and vinblastine, were evaluated for their effects on producing meiotic arrest in the laboratory mouse. Colchicine is the most effective and its effect is both dose- and time-dependent. Treatment of mice with 40 mg/kg of colchicine for 3 h resulted in drastic improvement of the yield and quality of M-II figures. This treatment did not appear to increase the aneuploidy frequency in M-II's.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01964819
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