ISSN:
1435-1463
Keywords:
ECS
;
dopamine release
;
opioids
;
striatum
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The fractional release technique was applied to investigate the effects of single electroshock (ECS) on the opioid-mediated inhibition of dopamine release in rat striatal slices. Animals were submitted to ECS 24h before the experiments. The results demonstrate that pre-treatment with ECS suppresses the inhibition of dopamine release mediated by κ opioid receptors. These data suggest that single ECS treatment modifies the sensitivity of the κ opioid receptors located on the presynatic dopamine terminals in the rat striatum.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01285549
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