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  • 1
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 4 (1975), S. 0 
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The influence of macrophages on polyclonal B-cell responses to lipopolysaccharide (LPS) and on a primary, specific immune response to a hapten-LPS conjugate was studied in mouse spleen and lymph node cells in serum-free and serum-supplemented cultures. Macrophages were found not to be necessary, and B cells were directly activated by LPS. In serum-free cultures of macrophage depleted spleen cells, (a) proliferation and antibody secretion occurred at normal levels or were enhanced when compared with normal spleen cells, (b) the responsiveness of limiting cell numbers to LPS was better than in normal spleen cell cultures, (c) LPS did not increase the number or activate residual macrophages, (d) the primary specific response to a hapten-LPS conjugate developed normally, (e) peripheral lymph node cells, which are known to contain a very low concentration of macrophages, from normal or congenitally athymic (nude) mice mounted excellent proliferative responses to LPS Furthermore, in cultures supplemented with fetal bovine serum, depletion of adherent cells resulted in enhancement of LPS-induced B-cell responses. Addition of peritoneal macrophages to adherent cell-depleted spleen cells produced suppression at all concentrations of both mitogen and adherent cells. Suppressive activity could also be demonstrated in supematants from adherent cell cultures stimulated by LPS
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 5 (1976), S. 0 
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The primary immune response to sheep erythrocytes in adherent cell-depleted cultures was restored by adding a critical number of peritoneal ceils. Complete substitution was achieved also with supernatants from allogencic and syngeneic peritoneal cells. Both living fibroblasts and supernatants from fibroblast cultures were found to be highly efficient substitutes for adherent cells in both syngeneic and allogeneic systems. Supernatants from non-antigen-treated peritoneal cells and fibroblasts caused increased DNA synthesis and induction of polyclonal antibody synthesis in normal spleen cells. Thus, adherent cells need not function in the immune response by presenting antigen to the B cells via ‘IgT’ or by releasing signal-2 activity, which acts on lymphocytes that have already received signal 1.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Aquaculture research 30 (1999), S. 0 
    ISSN: 1365-2109
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: This research assessed the effects of two chemicals, cypermethrin (Excis) and azamethiphos (Salmosan), used in the treatment of sea lice Lepeophtheirus salmonis (Kroyer) on American lobster Homarus americanus H. Milne Edwards larvae under laboratory conditions. Larvae were exposed to concentrations of 5, 0.5, 0.05, 0.005 and 0 p.p.b. cypermethrin and 100, 10, 1, 0.1 and 0 p.p.b. azamethiphos for durations of 5, 30 and 60 min, 6 and 12 h in artificial seawater. Both treatment chemicals caused significant mortality (P 〈 0.05) of the lobster larvae below the recommended treatment doses of 5 p.p.b. cypermethrin for 1 h and 100 p.p.b. azamethiphos for 1 h. Temperature affected mortality significantly (P 〈 0.05). and interactions between treatment duration and treatment concentration were also significant (P 〈 0.05). LC50 values calculated for the treatment durations ranged from 0.66 to 0.058 p.p.b. at 10 °C and 1.69–0.365 p.p.b. at 12 °C for cypermethrin, and 33.9–1.3 p.p.b. at 10 °C and 50.4–0.9 p.p.b. at 12 °C for azamethiphos treatment, at the above treatment durations. The lowest LC50 values correspond to ≈ 1/90th of the recommended treatment dose for cypermethrin (Excis) at 12 °C and 1/14th at 10 °C; and 1/110th of the recommended treatment dose for azamethiphos (Salmosan) at 12 °C and 1/75th at 10 °C. The research determined variations in observed behavioural treatment effects on lobster larvae exposed to both cypermethrin and azamethiphos (temperature × treatment duration × treatment concentration; cypermethrin P 〈 0.001, azamethiphos P = 0.008). The pattern of effects that occurred at each temperature were, however, similar (cypermethrin P = 0.764; azamethiphos P = 0.218), and ‘intensity of effect’ of the treatment chemicals was positively correlated with an increasing treatment concentration high (r2 = 0.915, r2 = 0.905).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    facet.materialart.
    Unbekannt
    Berlin : Periodicals Archive Online (PAO)
    Orientalistische Literaturzeitung. 42 (1939) 636 
    ISSN: 0030-5383
    Thema: Allgemeine und vergleichende Sprach- und Literaturwissenschaft. Indogermanistik. Außereuropäische Sprachen und Literaturen , Ethnologie , Geschichte
    Notizen: Besprechungen
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Journal of Molecular and Cellular Cardiology 9 (1977), S. 29-30 
    ISSN: 0022-2828
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    European food research and technology 27 (1914), S. 713-723 
    ISSN: 1438-2385
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 180 (1962), S. 732-738 
    ISSN: 1434-4726
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 205 (1973), S. 221-225 
    ISSN: 1434-4726
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 207 (1974), S. 527-535 
    ISSN: 1434-4726
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Serous Otitis media or Mucoserotympanon is a desease of the middle ear mucosa following tubal dysfunction. In the antibiotic aera it has become one of the most frequent causes for deafness in children, the tendency in adults is increasing. In two thirds of the children adenoidectomy and paracentesis is sufficient for treatment, one third needs application of a ventilation tube. In adults paracentesis and retrograde tubal ventilation can be done without anaesthesia. In elderly people therapy resistent fluid accumulation in the middle ear might be provoked by a mucocele or a tumor of the epipharynx.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 210 (1975), S. 347-348 
    ISSN: 1434-4726
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The influence of tonsilleetomy and adenotomy on tube function was examined in 100 children ranging from 2 years to 12 years of age. The measurements were performed by tympanometry during 6 days after the operation. The results were put into relation to the pressure values found before operation. In cases with normal middle ear pressure values these declined on the first day after operation down to values below 150 mm (watergauge) normalizing within the following 5 days. In cases with preoperative fluid in the middle ear the tympanogram would mostly not normalize after adenotomy. The results of these examinations give rise to consequences to the therapeutic procedure. 1. The adenotomy never should be performed together with tympanoplastic surgery. Otherwise the subpressure values after adenotomy may lead to adhesive processes. 2. As middle ear fluid will not be absorbed after adenotomy alone tubes should be inserted into the tympanic membrane.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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