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  • 1
    ISSN: 1432-2307
    Schlagwort(e): Ewing's sarcoma ; Bone ; Histology ; Prognosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A retrospective multifactorial analysis on 261 previously untreated patients with Ewing's sarcoma (Es) of bone has been carried out in order to ascertain the prognostic value of several histological variables on survival. Among those cases accepted as Es, 208 (80% of the patients) were considered to be “typical Es”, while 40 (15%) displayed a large cell predominance, being subclassified as “atypical large cell Es”. Furthermore, 13 patients (5%) possessed tumours of endothelial-like appearance. Eleven cases which displayed a mixed histological configuration were finally included within one of the three previous groups according to their predominant histological pattern. After adjustment for therapeutic regimens and initial location of the tumour, only two histological characteristics remain significant; i.e. the presence of necrosis (p=0.002) and, to a lesser degree, the presence of filagree “en damier” pattern (p=0.08), both of which are of poor prognostic value. From this study, it can be assumed that the morphological (and possibly histogenetical) heterogeneity of Es of bone has no prognostic influence on survival.
    Materialart: Digitale Medien
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  • 2
    ISSN: 1432-2161
    Schlagwort(e): Osteosarcoma ; Local evaluation ; Chemotherapy ; Computed tomography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Forty-eight, computed tomography (CT) examinations undertaken in 30 patients with osteosarcoma of long bones were studied in detail, their diagnostic information being compared with that obtained from corresponding plain films. The latter were of more value in assessing peripheral bony involvement, by cortical extension and periosteal reaction, while the former, in general, permitted more accurate observation of extensions into adjacent soft tissues. Recognition of such extensions, however, was vitiated when they arose in relation to the proximal ends of the tibia, fibula, and humerus and when a haematoma had developed as a result of a biopsy. Plain films were also of more value in appreciation of response to chemotherapy. On the other hand CT is the only examination which permits a satisfactory study of intramedullary extensions of the tumour and in consequence is invaluable in determining the exact sites required for local resection. No cases of skip metastases were observed in our series, although similar appearances due to nutrient vessels or bony ridges, remote from the primary tumour, were noted on several occasions. Differentiation of these densities proved to be easy, particularly in the case of nutrient vessels when examination of the contralateral bone showed them to be symmetrical. Several authors have described the role of CT in the evaluation of local extensions. This paper reports the difficulties and errors encountered by us.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Skeletal radiology 16 (1987), S. 196-200 
    ISSN: 1432-2161
    Schlagwort(e): Telangiectatic osteosarcoma ; Bone tumors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Fourteen telangiectatic osteosarcomas are reported. They are rare, clinically and radiologically aggressive lesions, involving mainly the femurs of young patients, often misdiagnosed as aneurysmal bone cysts. An explanation for a characteristic early radiological appearance consisting of regular parallel striations of the shaft is suggested.
    Materialart: Digitale Medien
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  • 4
    ISSN: 1432-5195
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé Le traitement chirurgical avec instrumentation postérieure de «Cotrel-Dubousset» (C. D.) des cyphoses et des cypho-scolioses chez l'enfant ou l'adolescent a souvent réclamé un temps antérieur complémentaire soit précédant, soit suivant le temps postérieur. Nous avons revu 20 enfants ou adolescents opérés et suivis à l'Hôpital Saint Vincent de Paul à partir de 1983. Quatre points particuliers se sont avérés prédominants pour le choix des indications thérapeutiques: l'étiologie, la maturation, l'angularité et la souplesse persistante du rachis cyphotique en hyperextension sur le billot. La préparation par traction pré-opératoire (pour une durée moyenne de 25 jours) a apporté un gain supplémentaire de 14% sur la correction finale. Elle a été réservée aux cyphoses les plus prononcées, en général plutôt hautes, thoraciques, ne bénéficiant pas de la souplesse du rachis lombaire et dont le caractère prédominant est la raideur sur le billot. Le temps antérieur n'est pas indiqué pour les scolio-cyphoses doubles dorsolombaires à grand rayon, restées souples, et volontiers d'origine idiopathique juvénile chez des enfants déjà parvenus à un stade avancé de maturation. Il est nécessaire dans les grandes cyphoses angulaires caractérisées soit par l'instabilité, soit par la raideur antérieure. Il peut être discuté pour les jeunes cypho-scolioses et les scolio-cyphoses. La correction obtenue sur la cyphose a été de 73% pour les cyphoses pures, de 66% pour les cypho-scolioses et de 59% pour les scolio-cyphoses. Les suites ont été en général simples, permettant une verticalisation précoce sans protection par un corset.
    Notizen: Summary The surgical treatment of kyphosis and kyphoscoliosis in children or adolescents using the Cotrel-Dubousset (C. D.) instrument through a posterior approach may often need a further anterior procedure either before or after. We have reviewed 20 adolescents who were operated on at l'Hôpital Saint Vincent de Paul since 1983. Our choice of management was determined by consideration of the aetiology, the age, the degree of angulation and the suppleness of the kyphotic spine in hyperextension on the operating table. The use of preoperative traction for a mean of 25 days gained an improvement of 14% of the final correction. It was used in the curves which were most pronounced, usually high thoracic curves which lacked suppleness in the lumbar spine and which were stiff on the table. The anterior approach was not indicated in long double dorso-lumbar curves, usually of idiopathic origin, which had already reached an advanced stage of development. It was necessary in severe angular kyphoses which were unstable or had marked anterior stiffness. It was sometimes used in younger patients with kyphoscoliosis in which it was difficult to assess the state of maturity. After operation the kyphosis was corrected by up to 73% in simply kyphoses, 66% in kyphoscoliosis and 59% in scolio-kyphosis. After operation we were usually able to mobilise patients without a corset.
    Materialart: Digitale Medien
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  • 5
    ISSN: 1432-2307
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    European spine journal 3 (1994), S. 120-125 
    ISSN: 1432-0932
    Schlagwort(e): Hemivertebrae ; Progressive congenital scoliosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Six patients aged ≤ 5 years with congenital scoliosis due to vertebral malformation were treated by anterior and posterior epiphysiodesis of the convexity. In all cases the pattern of deformity was a kyphoscoliosis. The average age at operation was 3 years 6 months, average follow-up was 4 years 6 months, and average preoperative angles were 42° in the frontal and 36° in the sagittal plane. The fusion included the malformative zone and the supe rior and inferior adjacent vertebrae. Two patients had a fusion effect, three patients had a true epiphysiodesis effect, and one patient had a postoperative progression of the deformity. Epiphysiodesis of the convexity is a treatment proper for the growing period, allowing the child either to reach skeletal maturity without needing further treatment or to achieve an adequate torso height to finish the treatment with a classical vertebral arthrodesis.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1432-0932
    Schlagwort(e): Scoliosis ; Crankshaft phenomenon
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The aim of this study was to determine whether an anterior approach to the spine with a fusion of the growth centers of the anterior column of the spine, simultaneous by with a posterior fusion and instrumentation of the spine, in young patients with severe scoliosis who have considerable remaining growth, leads to prevention of the crankshaft phenomenon. Twelve patients who have had anterior fusion of the spine associated with posterior fusion and instrumentation of the spine were studied. In 10 of them, growth progression was demonstrated by modification of the Risser sign; for these patients no important progression of the spinal deformity was noted. One patient had no progression of the Risser sign and no progression of spinal deformity. One patient had progression of spinal deformity due to the disruption of the sacral anchorage of instrumentation. We think that this procedure leads to the prevention of the crankshaft phenomenon, and we recommend this procedure in young patients with severe scoliosis and considerable remaining growth. It must include all intervertebral levels of the rigid segment of the curve.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    European spine journal 4 (1995), S. 194-199 
    ISSN: 1432-0932
    Schlagwort(e): CDH (Cotrel-Dubousset-Hopf) ; Primary stability ; Mono-and multisegmental anterior device
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary CDH (Cotrel-Dubousset-Hopf) instrumentation was developed with the aim of improving stability in ventral operation procedure and facilitating treatment of all anterior spinal diseases. The implantation of anterior plates and drawers, the use of a double-rod fixation within the implant in nonparallel directions, which provide an automatic locking mechanism against displacement, the prevention of dislocation of the cancellous bone srews, and the crosslink principle are its main characteristics. The device can be applied to the spine in accordance with its three-dimensional anatomy by any kind of force (distraction, compression, and rotation). Additional posterior instrumentation and postoperative external support are unnecessary in most cases because of improved stability. No reoperation was necessary following the mono- and multisegmental application of this method in 60 patients (28 with scoliosis, 12 with spondylodiscitis, 8 with primary tumors or isolated metastasis, 6 with fractures, 3 with failed back syndrome, 1 with kyphotic deformity, 1 with spondylolisthesis on two levels, and 1 with loss of correction after the dislocation of another posterior spinal instrumentation). Average blood loss was 950 ml; the average operating time was 3 h. In all, 16 monosegmental and 44 multisegmental procedures were carried out. In 25 patients, in particular those with paralytic scoliosis, a double-stage anterior and posterior spondylodesis was done.
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 21 (1999), S. 7-9 
    ISSN: 1279-8517
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Conclusion L'utilisation de segments longs conservant une mobilité du sacrum avec des sollicitations mécaniques faibles est possible. De telles pièces anatomiques doivent permettre d'évaluer le comportement de la transition lombo-sacrée ainsi que des art. sacro-iliaques au cours d'ostéosynthèses étendues au sacrum.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 21 (2000), S. 377-381 
    ISSN: 1279-8517
    Schlagwort(e): Sacroiliac ; Mobility ; Vertebral column ; Biomechanics
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Six fresh human specimens extending from the 9th thoracic vertebra (T9) to the pelvis were used to study the biomechanical behaviour of the long lumbopelvic segments, including mobility of the sacrum. The loads were applied at T9 using pure couples up to 5Nm. The displacements were measured by an optoelectronic method (VICON 140). Stress-displacement curves were obtained for the three angular components of the vertebra studied according to the plane of the principal stresses and of the two other planes corresponding to the coupled mobilities. Mobility decreased from T9 to the sacrum. There was mobility of the sacrum in relation to the pelvis in flexion, with a mean of 1.28° (0.5 to 2.8°) 3 sacrums showed a mobility of the order of one degree for torsional stresses. There was no sacral mobility during stresses in lateral flexion. The use of this experimental protocol with low mechanical stresses should allow the evaluation of long osteosyntheses extending to the sacrum.
    Materialart: Digitale Medien
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