Library

X
You have 0 saved results.
Mark results and click the "Add To Watchlist" link in order to add them to this list.
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Quantitative structure-pharmacokinetic relationships derived on antibacterial sulfonamides in rats and its comparison to quantitative structure-activity relationships (1980)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 23 (1980), S. 607-613 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm00180a005
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Fast method for the simultaneous determination of 2-oxo acids in biological fluids by high-performance liquid chromatography
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 662 (1994), S. 97-102 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-4347(94)00383-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    O"2 Consumption and K^+/Na^+ balance of elasmobranch kidney slices after replacement of urea by thiourea or acetamide
    Amsterdam : Elsevier
    Comparative Biochemistry and Physiology -- Part A: Physiology 47 (1974), S. 271-275 
    Details
    ISSN: 0300-9629
    Keywords: Oxygen consumption ; acetamide ; elasmobranch metabolism ; thiourea
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0300-9629(74)90070-X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The relationship between gas and ion transfer across the gills of fishes
    Amsterdam : Elsevier
    Comparative Biochemistry and Physiology -- Part A: Physiology 41 (1972), S. 629-637 
    Details
    ISSN: 0300-9629
    Keywords: Fish gills ; Salmo gairdneri ; Trout ; ^2^2Na ; adrenaline ; gas transfer ; gills ; isoprenaline ; noradrenaline ; respiration ; vascular resistance
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0300-9629(72)90017-5
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    The effect of urea, thiourea and acetamide on the renal and branchial enzyme-pattern of the dogfish Scyliorhinus canicula
    Amsterdam : Elsevier
    Comparative Biochemistry and Physiology -- Part B: Biochemistry and 54 (1976), S. 177-179 
    Details
    ISSN: 0305-0491
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0305-0491(76)90078-X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Acute changes of the Na−K-ATPase-activity in plasmamembranes of the isolated, cell-free perfused rat kidney (1975)
    Springer
    Pflügers Archiv 353 (1975), S. 97-106 
    Details
    ISSN: 1432-2013
    Keywords: Isolated Kidney ; Plasmamembranes ; Na−K-ATPase ; Na-Reabsorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The Na−K-ATPase-activity of the isolated, cell-free perfused rat kidney was investigated. Na-load and perfusion rate could be varied independently. The ATPase-assay was carried out on plasmamembranes (700–1200 g fraction) isolated and purified after 60 min perfusion. Both the specific Na−K-ATPase-activity and the fractional Na-reabsorption showed an indirect correlation with the Na-load as well as with the perfusion rate. The Na−K-ATPase-activity of plasmamembranes obtained from the isolated kidney at physiological Na-load fits well to control values prepared from unperfused control kidneys. The present data are in accord with the results of earlier micropuncture experiments, where acute saline loading diminished the rate of Na-reabsorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00599871
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    The effect of dietary sodium on the renal enzyme-pattern of the rat (1973)
    Springer
    Pflügers Archiv 339 (1973), S. 339-348 
    Details
    ISSN: 1432-2013
    Keywords: Dietary Sodium ; Renal Enzyme Pattern
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The relationship between dietary sodium and the activity of representative renal enzymes of the three main metabolic pathways-oxydative breakdown, glycolysis and pentose-monophosphate-shunt-was studied in the rat kidney. Enzyme assays were carried out on total tissue homogenates and isolated mitochondria of the cortex and medulla as well as on isolated glomerula of rats maintained on low or high sodium diet for 14–17 days. While there was no difference in the weight-gain between rats maintained on low sodium food or normal laboratory chow, rats fed high sodium diet put on more weight and had larger kidneys than the other groups. The protein content of the total tissue homogenate followed the same pattern whereas equal amounts of mitochondrial or glomerular protein was found in all three groups. In all preparations both low, and to a greater extent, high dietary sodium increased the specific activity of the majority of enzymes assayed. No fall in the activity of any enzyme could be observed. A number of causal mechanisms are discussed. It is assumed that hyperaldosteronism in the low-sodium group and elevated vasopressin level in rats fed high-sodium diet are responsible for the identical results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00594168
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Nierenfunktion bei Ratten mit experimentellem DOCA-Hochdruck (1972)
    Springer
    Pflügers Archiv 332 (1972), S. 28-39 
    Details
    ISSN: 1432-2013
    Keywords: Kidney ; Experimental Hypertension ; DOCA ; Specific Reabsorption Capacity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rats were made chronically hypertensive by unilateral nephrectomy, repeated injections of desoxycorticosterone-acetate and offering saline as drinking fluid (DOCA-rats). Unilaterally nephrectomized animals (Nephrex-rats) were used for control. Compensatory renal hypertrophy was greater in DOCA-rats than in Nephrex-rats. Diameter and length of the proximal convolute in the DOCA-group increased more than in Nephrex-rats. GFR per unit kidney weight in the DOCA-group remained unchanged as compared to untreated Wistar-rats but increased significantly in Nephrex-animals. the water and sodium load of each nephron had doubled in both groups. Nevertheless, there were no substantial changes in the fractional water and sodium reabsorption in the different segments of the nephron of DOCA-rats as compared to normal animals. In Nephrex-rats fractional sodium and water reabsorption were increased in the proximal tubule and diminished in the loop of Henle and in the distal tubule. In Nephrex-rats an indirect correlation was found between blood pressure and both water reabsorption and the transit time of Lissamine green in superficial loops of Henle but no such correlation could be found in the DOCA-group. Determination of the specific reabsorption capacity of the proximal tubules during free-flow or using the split-drop technique yielded identical values in all animals studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00603812
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    N-acetylation of p-amino-hippurate in kidneys with renal artery stenosis and in patients suffering from severe essential hypertension (1974)
    Springer
    Journal of molecular medicine 52 (1974), S. 913-915 
    Details
    ISSN: 1432-1440
    Keywords: PAH ; PAH-metabolism ; N-acetylation ; renal artery stenosis ; essential hypertension ; PAH ; PAH-Metabolismus ; N-Acetylierung ; Nierenarterien-Stenose ; essentielle Hypertonie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Routinemäßige PAH-Clearance-Untersuchungen wurden durchgeführt bei Patienten mit a) Glomerulonephritis, b) sekundärer Beeinträchtigung der Nierenfunktion, c) essentieller Hypertonie und d) bei Patienten mit einseitiger Nierenarterien-Stenose. Die renale Ausscheidung von N-Acetyl-PAH war signifikant erniedrigt bei Patienten mit Nierenarterien-Stenose oder mit essentieller Hypertonie, während die anderen Gruppen keine Störung des PAH-Metabolismus aufwiesen. Die Bedeutung dieser Befunde wird diskutiert.
    Notes: Summary Routine PAH-clearance studies were carried out on patients with (a) glomerulonephritis, (b) secondary impairment of renal function, (c) essential hypertension, and (d) patients with unilateral renal artery stenosis. Renal excretion of N-acetyl-PAH was significantly lower in patients with unilateral artery stenosis or with essential hypertension, while the other groups showed no impairment of the PAH-metabolism. The implications of these findings are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468936
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Die Wirkung von vasodilatatorischen Substanzen (Papaverin, Acetylcholin) auf die Nierenfunktion (1964)
    Springer
    Pflügers Archiv 281 (1964), S. 346-355 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Nach Infusion von 20 mg/min Papaverin während 10 min in die Arteria renalis nimmt die durch die Niere strömende Blutmenge zu. Beträchtlich erhöhen sich die Na-Ausscheidung und Diurese. Gleichzeitig kommt es zu einer starken Verminderung der PAH-Clearance und -Extraktion, sowie der Kreatinin-Clearance und -Extraktion. Die Vermehrung der Nierendurchblutung bei vermindertem Glomerulumfiltrat ist wahrscheinlich auf den sich in erster Linie an den efferenten Arteriolen manifestierenden dilatatorischen Effekt von Papaverin, die Senkung der PAH-Clearance und -Extraktion, sowie der Na-Reabsorption ist auf seine toxische Nebenwirkung zurückzuführen. Die Möglichkeit des Kurzschlusses des Nierenkreislaufs bei Papaverin kann jedoch mit Bestimmtheit nicht ausgeschlossen werden. Mit 0,5 mg/min Acetylcholin, während 10 min in die Arteria renalis infundiert, wurde die durch die Niere strömende Blutmenge bedeutend gesteigert. Dabei zeigen PAH- und Kreatinin-Clearance bzw. -Extraktion keine wesentliche Veränderung, d. h. unter Acetylcholinwirkung tritt eine bedeutende Abweichung zwischen den auf Grund der Clearance errechneten und den direkt gemessenen RBF-Werten zutage, was auf die vermehrte Lymphbildung und Lymphströmung zurückgeführt wird. In der verabreichten Menge bewirkt das Acetylcholin keine Veränderung der Na-Ausscheidung und Diurese.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00362356
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...