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  • 1
    Electronic Resource
    Electronic Resource
    Effect of nitrate esters of androgen steroids on the succinate oxidase and NADH-Cytochrome C reductase activity of isolated rat liver mitochondria (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 820-821 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Le testostérone et la 5α-androstane-17β-ol-3-one stimulent l'activité de la succinoxydase des mitochondries intactes et l'activité de la NADH-cytochrome-c-réductase des mitochondries à membranes lésées, extraites du foie du rat blanc. Les nitrates-esters des mÊmes stéroÏdes réduisent l'activité des deux enzymes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01897896
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Biologie du chinchard de la Mer Noire (Trachurus meditarraneus ponticus) (1967)
    Springer
    Marine biology 1 (1967), S. 33-35 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé 1. On a étudié l'action directe de l'hydrocortisone, de la testostérone et de l'estradiol sur l'activité de la succinedèshydrogénase (SDH) et de la cytochromeoxydase (CyOx), sur la consommation de l'oxygène et sur la production de l'acide lactique et pyruvique par les coupes tissulaires du foie et de la rate chez le chinchard (Trachurus meditarraneus ponticus). 2. L'hydrocortisone en concentration de 10-4 M, diminue la consommation d'oxygène et l'activité de la CyOx et de la SDH. Cette hormone augmente fortement la production de l'acide lactique par les coupes tissulaires du foie et de la rate. 3. La testostérone détermine une diminution de la production de l'acide lactique, et augmente l'activité de la SDH et la consommation de l'oxygène. 4. L'estradiol diminue l'activité de la CyOx du foie et la production de l'acide lactique. 5. On peut conclure que pour les oxydations intracellulaires et la glycolyse dans le foie et la rate du chinchard, l'hydrocortisone est un antagoniste de la testostérone et de l'estradiol.
    Notes: Abstract A study has been made regarding the action of the hydrocortisone, testosterone and 17β-estradiol on isolated liver and spleen tissue homogenates or slices of male and female adults of the fish Trachurus mediterraneus ponticus. The results showed a decrease of the oxygen uptake and of the cytochrome oxydase and succinic dehydrogenase activity of the liver homogenate after hydrocortisone administration, while this hormone increased significantly the lactic acid production in both tissues. Testosterone acted in an opposite manner to hydrocortisone by increasing the intensity of oxygen consumption and the succinic dehydrogenase activity, but decreased the lactic acid production of the liver and spleen tissue preparations. Estradiol decreased the oxygen consumption of the liver, the cytochrome oxydase activity and the lactic acid production in both tissues of female Trachurus mediterraneus ponticus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00346691
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    L-tyrosine: 2-oxoglutarate aminotransferase induction by hydrocortisone in the thymus of the white RAT (1975)
    Springer
    Molecular and cellular biochemistry 9 (1975), S. 131-133 
    Details
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Hydrocortisone hemisuccinate within 4 hours afterin vivo administration produces an increase in precursor incorporation into rat thymus RNA and proteins in the whole animal. From these results, together with information obtained from measurements of the tyrosine aminotransferase activity and the action of mitomycin C administered one hour before the injection of hydrocortisone, it can be concluded that the increase in tissue level of the enzyme, consequent to hydrocortisone treatment, results from an increased rate of biosynthesis of the enzyme, which participates in the catabolic processes of proteins in glucocorticoid sensitive thymus cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01751307
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  • 4
    Electronic Resource
    Electronic Resource
    ‘3H-testosterone distribution and binding in RAT thymus cells in vivo’ (1976)
    Springer
    Molecular and cellular biochemistry 13 (1976), S. 157-163 
    Details
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Autoradiography and biochemical investigations showed that [3H]-testosterone where injected intraperitoneally into male white rats was incorporated rapidly into thymus lymphocytes. Thymic cortex contained more silver grains than medulla, and larger lymphocytes were more labelled than medium or small lymphocytes. Cytosol fraction of thymus cells labelledin vivo with [3H]-testosterone, contained the largest quantity of labelled hormone. A 4S cytosol fraction binds [3H]-testosterone. This could be separated by Sephadex chromatography or by linear sucrose gradient centrifugation. Nuclear extract contained also a small quantity of the labelled hormone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01731778
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Gas chromatographic study of some local anesthetics (1989)
    Springer
    Chromatographia 28 (1989), S. 24-26 
    Details
    ISSN: 1612-1112
    Keywords: Gas chromatography ; Anesthetics ; Pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A sensitive capillary gas chromatographic method is described for the simultaneous determination of lidocaine, tetracaine, procaine and dibucaine. The method was applied to the determination of anesthetics in tissue homogenates incubated at 38°C at doses between 10 and 400 mg/kg. In the liver tissue thein vitro metabolization of the studied anesthetics is most rapid for tetracaine, also fast for procaine, while for lidocaine and dibucaine the metabolization is very slow. In brain tissue thein vitro metabolization of anesthetics is very slow. The method shows good analytical parameters: linearity between 5 and 40 μg/ml; day-to-day reproducibility ca. 8% for a concentration of 20 μg/ml, precision ca. 7% for a concentration of 20μg/ml. Accuracy is also very good.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02290377
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    Paper (German National Licenses)
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