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  • 1
    Electronic Resource
    Electronic Resource
    Renal replacement therapy in Down's syndrome (1993)
    Springer
    Pediatric nephrology 7 (1993), S. 771-771 
    Details
    ISSN: 1432-198X
    Keywords: Down's syndrome ; Renal replacement therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01213350
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pediatric dialysis transplant registries (1994)
    Springer
    Pediatric nephrology 8 (1994), S. 646-646 
    Details
    ISSN: 1432-198X
    Keywords: Renal replacement therapy ; Canada
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00858155
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Cyclosporin A in children with persistent renal transplant rejection and progressively deteriorating graft function (1987)
    Springer
    Pediatric nephrology 1 (1987), S. 140-144 
    Details
    ISSN: 1432-198X
    Keywords: Cyclosporin A ; Persistent renal transplant rejection ; Azathioprine ; Renal function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect on renal function and growth of switching from azathioprine to cyclosporin A (CyA) was prospectively evaluated in ten children with persistent renal transplant rejection. Progression of renal insufficiency during CyA therapy was compared with that before using CyA. Prednisone administration decreased after CyA was introduced and although growth retardation persisted, height velocity improved significantly. Renal function stabilized in seven patients treated with CyA for a variable time period, and four of these children remain off dialysis 0.44–1.42 years later. Renal biopsies were obtained in seven children when they were converted from azathioprine to CyA. The response to CyA could not be predicted from renal morphology or clinical features.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00849284
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Non-steroidal anti-inflammatory drug-associated nephrotoxicity in Bartter syndrome (1998)
    Springer
    Pediatric nephrology 12 (1998), S. 775-777 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Bartter syndrome ; Nephrotoxicity ; Non-steroidal anti-inflammatory drugs ; Creatinine clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We have followed four patients with Bartter syndrome for a mean of 25.4 years (range 21.5–28.8 years) after diagnosis. All patients received non-steroidal anti-inflammatory drugs (NSAID). In all patients, various degrees of renal dysfunction were noted to be temporally associated with NSAID therapy. In two patients, renal dysfunction resolved after discontinuing NSAID therapy, while maintaining other chronic medications such as potassium-sparing diuretics. Renal dysfunction persisted after NSAID withdrawal in two patients. We report these cases as a warning that NSAID should be considered an important cause of either reversible or irreversible renal dysfunction in Bartter syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050545
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Cardiomyopathy: a late complication of hemolytic uremic syndrome (1997)
    Springer
    Pediatric nephrology 11 (1997), S. 221-222 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Hemolytic uremic syndrome ; Cardiomyopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. This report describes a child who presented with classic hemolytic uremic syndrome (HUS) and 4 months later developed a life-threatening but reversible cardiomyopathy with global cardiac dysfunction and a left ventricular ejection fraction of 14%. There was no evidence of electrolyte abnormalities, anemia, hypertension, severe fluid overload, or viral infection. Endomyocardial biopsies were consistent with a dilated cardiomyopathy. This paper highlights the importance of considering the diagnosis of associated cardiomyopathy when presenting with late-onset edema following HUS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050267
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  • 6
    Electronic Resource
    Electronic Resource
    Survival of cadaveric renal transplant grafts from young donors and in young recipients (1991)
    Springer
    Pediatric nephrology 5 (1991), S. 152-157 
    Details
    ISSN: 1432-198X
    Keywords: Cadaveric renal transplant ; Young donor ; Young recipient ; Renal thrombosis ; Ischemia ; Technical problems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Evidence from multicenter registries has suggested that cadaveric renal graft survival is poorer when either the recipient or the donor is very young. We therefore analyzed our results from a single pediatric center. There was a significant correlation between greater recipient age and improved cadaveric graft (P=0.002) and patient (P=0.0009) survival. The age of the donor also appeared important, particularly in very young children, but became less so as donor age rose. Forty-four percent of recipients under 3 years old who received cadaveric kidneys from donors less than 4 years old lost their grafts as a result of renal thrombosis, ischemia, or technical problems, compared with only 3% of recipients over 9 years of age, whose grafts came from donors who were also over 9 years. The 1-year first cadaveric graft survival rates for these two age groups were 33% and 82% respectively. Our experience confirms the poor findings reported in very young recipients and with very young donors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00852874
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Renal transplantation in children (1993)
    Springer
    Pediatric nephrology 7 (1993), S. 184-184 
    Details
    ISSN: 1432-198X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00864392
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Long-term neurological sequelae of hemolytic-uremic syndrome: a preliminary report (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 504-506 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Hemolytic uremic syndrome ; Neurological outcome ; Cognitive outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Seven patients with hemolytic-uremic syndrome who had major neurological symptoms during the acute illness were neurologically and cognitively evaluated prospectively several years after recovery from the illness. Four patients showed evidence of subtle neurological sequelae, including posturing, clumsiness, poor fine-motor coordination, hyperactivity, and distractibility. Psychoeducational evaluation of all seven subjects revealed mean scores within the average range in cognitive abilities, academic achievement, single word receptive vocabulary, visual/motor planning, overall adaptive functioning, and hyperactivity. The lapse of time (minimum of 7 years) between the acute illness and the psychometric evaluation could have been responsible for our normal results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050150
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  • 9
    Electronic Resource
    Electronic Resource
    Compliance with cyclosporine in adolescent renal transplant recipients (1997)
    Springer
    Pediatric nephrology 11 (1997), S. 547-551 
    Details
    ISSN: 1432-198X
    Keywords: Key words:  Compliance ; Cyclosporine ; Renal transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract.   Inadequate compliance with prescribed medication regimens in children is complex and poorly understood. We measured the extent and pattern of noncompliance with cyclosporine in our adolescent renal transplant population and attempted to determine factors associated with poor compliance. After informed consent, each patient was provided cyclosporine capsules in a medication bottle equipped with an electronic monitoring device (MEMS-4) in the lid. Of the 24 patients eligible, 19 patients (8 female, 11 male) completed the study. Four (21%) patients took less than 80% of the prescribed cyclosporine doses. Five (26%) patients took drug holidays involving ≥3 consecutive doses. There was a trend towards improved compliance with the evening dose (88.5% vs. 93.4%, P = 0.09) and a downward trend in compliance over the course of the study (P = 0.17). None of the variables tested were found to be associated with noncompliance. Experienced physicians and nurses were able to identify 2 of the 4 individuals who were identified by MEMS as noncompliant. Additionally, 2 of the 4 noncompliant patients demonstrated low cyclosporine trough levels (〈50 ng/ml). Noncompliance with cyclosporine regimens occurs commonly in adolescent renal transplant recipients. Unexpectedly low cyclosporine levels are strongly suggestive of noncompliance, whereas other variables, including prediction by physicians and nurses intimately involved in the care, were not reflective of noncompliance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050335
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  • 10
    Electronic Resource
    Electronic Resource
    A family outbreak of hemolytic-uremic syndrome associated with verotoxin-producingEscherichia coli serotype 0157:H7 (1988)
    Springer
    Pediatric nephrology 2 (1988), S. 409-414 
    Details
    ISSN: 1432-198X
    Keywords: Hemolytic-uremic syndrome ; Verotoxin ; Escherichia coli ; Enteric infection ; Diarrhea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract All five siblings (three boys and two girls, aged 1.5–9 years) in a family developed hemolytic-uremic syndrome associated with verotoxin-producingEscherichia coli 0157:H7 at a lakeside vacation cottage during the fall of 1985. All five were hospitalized and made a full recovery. Both parents remained asymptomatic, and neither had evidence of this infection. In four children who were investigated prospectively, free verotoxin was still detectable in the stools for between 3 and 7 weeks. The prodromal diarrheal illness in the children occurred over a 10-day period. The epidemic curve was consistent with a point-source outbreak, but continuous exposure or person-toperson transmission could not be ruled out. The source of the infection was not identified.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00853433
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