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  • 1
    Electronic Resource
    Electronic Resource
    A simple ac susceptibility measuring system at low temperatures (1992)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 63 (1992), S. 4006-4007 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An automated ac susceptibility measuring system based on an ac mutual inductance bridge is described. A personal computer and a digital-analog converter are used to control the amplitude and phase of the compensatory signal which balances the bridge. An analog multiplier and a variable-resistance photocoupler are used in the amplitude and phase control circuits, respectively. The magnetic moment of a sample for a 1-μV output voltage is 3.8×10−6 emu/μV. Sufficient sensitivity was confirmed for an application to oxide superconductors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1143255
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  • 2
    Electronic Resource
    Electronic Resource
    The Radical Cation of Methylcyclohexane (1995)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 99 (1995), S. 12814-12821 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100034a021
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  • 3
    Electronic Resource
    Electronic Resource
    Influences of illumination intensity on the nearest neighbour distance in coho salmon Oncorhynchus kisutch (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 45 (1994), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Effects of illumination intensity on the nearest neighbour distance (NND) of coho salmon in an experimental aquarium were studied under illumination intensities ranging from 0 to 4000 Ix. The NNDs in sighted (intact) fish were divided into three groups according to the illumination intensities; the largest [1.15 times fork length (f.l.)] at 0 1x, the medium (0.78 to 0.84 f.l.) at 0.01 to 0.4 1x, and the least (0.60 to 0.66 f.l.) at 4–4000 1x. The fact that NNDs under 4 1x or higher illumination conditions were significantly smaller than those under 0.01 to 0.4 1x conditions suggests a change from photopic to scotopic vision. Blinded fish exhibited constant NNDs irrespective of illumination intensity and the value was similar to that of sighted fish under the 0 1x condition. The NNDs of blinded fish and sighted fish exposed to 0 1x were larger than the simulated NND calculated by hypothesizing that fish distribute randomly in the experimental aquarium. These results indicate that NND in a coho school is maintained primarily by vision, however, the NND is not determined by vision alone but by integrated senses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1994.tb01077.x
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  • 4
    Electronic Resource
    Electronic Resource
    IgE antibodies against midge and moth found in Japanese asthmatic subjects and comparison of allergenicity between these insects (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 52 (1997), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The specific IgE antibodies to moth (Bombyx mori) and midge (Chironomus yoshimatsui) were measured by the Pharmacia CAP system in 51 house-dust-mite-sensitive asthma patients. None of these patients had definite histories of exposure to these insects or apparent evidence of insect-induced asthma symptoms. The RAST-inhibition assay was performed to investigate cross-allergenicity between these two insects. Furthermore, IgE immunoblotting was done to study the IgE-binding components in moth and midge extracts. Thirty (59%) of these patients showed positive IgE antibodies to moth, while 25 (49%) showed positive IgE antibodies to midge. Those frequencies of positivity were similar to that for Japanese cedar pollen, which is well known to cause allergy. A significant correlation (r=0.863) was observed between IgE antibody liters of these two insects. The results from the RAST-inhibition assay indicated cross-allergenicity between these insects and also the existence of species-specific allergens. Fifteen IgE-binding components in moth extract were observed. The most frequent IgE-binding protein was the 79-kDa (84.2%), followed by the 72-kDa (78.9%), the 82-kDa (57.9%), and the 76-kDa (57.9%) proteins. Those were considered to be major allergens in moth. Twenty-four IgE-binding components in midge extract were observed. However, no IgE-binding protein to which over 50% of patient sera reacted was observed. These results suggest that these two insects may be considered to bear important allergens and that there is cross-allergenicity between these insects as well as species-specific allergens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1997.tb02548.x
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  • 5
    Electronic Resource
    Electronic Resource
    COMPARISON OF THE VASCULAR EFFECTS OF ADENOSINE, AMP, ADP AND ATP ON ISOLATED BLOOD-PERFUSED INTERNAL AND EXTERNAL CAROTID ARTERIES OF DOGS (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 7 (1980), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The effects of adenosine and adenine nucleotides were studied on arterial vasculature in blood-perfused arterial preparations of dogs which were isolated from the internal and external carotid arteries. Each compound was administered directly into the cannulated artery over a period of 4 s.2. In both arterial preparations, adenosine produced a dose-related vasodilatation and was more potent than AMP. On the other hand, ATP produced a dose-related vasoconstriction and was more potent than ADP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1980.tb00060.x
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of sample thickness on bite force studied with a multiple-point sheet sensor (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 31 (2004), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  The aim of this study was to investigate the relationship between thickness of sample food and bite force. We designed a new sensor that can detect the pressure distribution between the incisor and molar teeth on one side, and the contact area between the food samples and the teeth. The force and contact area were directly measured in real time using the multiple-point sheet sensor, which is a very thin and flexible pressure-sensing device. Silicone rubber blocks were used as a sample food and were chewed with incisors and molars by 10 healthy women. The peak force, contact area, duration and impulse were greater between the incisors for a thicker specimen. The active pressure, defined as the ratio of the force to contact area, at peak was similar for different thicknesses. In contrast, with a 2 mm thick sample, the peak force and force related parameters were greatest in molar chewing. The force, contact area and duration were greater for molar chewing cycles than incisor ones. We verified that the thickness of samples influenced the chewing force of humans and the effects differed between incisors and molars.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2003.01248.x
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  • 7
    Electronic Resource
    Electronic Resource
    Diversity of vacA and cagA genes of Helicobacter pylori in Japanese children (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 20 (2004), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Helicobacter pylori infection is generally acquired in childhood and persists as an asymptomatic infection for decades in most infected individuals. Only a minority develops a clinical outcome even in childhood, such as peptic ulcer. It has been reported that H. pylori infection with the type I strain, which expresses the VacA and CagA antigen, is associated with peptic ulcer.Aim : We examined the diversity of vacA and cagA genes in isolates obtained from Japanese paediatric patients with peptic ulcer or chronic gastritis to investigate the relationship between genetic diversity and clinical outcome.Methods : The diversity of vacA and cagA genes was investigated by PCR and sequence analysis in 30 isolates obtained from Japanese paediatric patients with peptic ulcer (eight strains) or chronic gastritis (22 strains).Results : All isolates from Japanese children were cagA-positive strains. Twenty-six strains (86.7%) had East Asian type CagA, and 4 (13.3%) had Western type CagA. The predominant vacA genotype was s1c/m1b (22/30, 73.3%). There was no significant association between the diversity of cagA and vacA genes and clinical outcome. All four children infected with Western CagA strain had a history of overseas travel or residence.Conclusion : The predominant genotype of H. pylori in Japanese children is East Asian CagA and vacA s1c/m1b genotype, regardless of clinical outcome. Japanese H. pylori strains are homogeneously of the East Asian type; however, Western strains can be introduced into Japan concomitant with host movement from foreign countries in childhood.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2004.01980.x
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  • 8
    Electronic Resource
    Electronic Resource
    The effects of cure of Helicobacter pylori infection on the signal transduction of gastric epithelial cells (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 18 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : The CagA protein of Helicobacter pylori is directly injected from the bacteria into cells via the bacterial type IV secretion system and undergoes tyrosine phosphorylation in the gastric epithelial cells. Translocated CagA forms a physical complex with the SRC homology 2 domain (SH2)-containing tyrosine phosphatase SHP-2, which plays an important role in mitogenic signal transduction in the host cells.Aim : We examined the effect of eradication therapy on the signal transduction pathway of gastric epithelial cells induced by the CagA protein of H. pylori.Methods : Gastric biopsy samples were obtained from 20 H. pylori-positive atrophic gastritis patients before, and 3 months after, H. pylori infection eradication therapy, and subjected to immunoblot analysis to detect tyrosine phosphorylated CagA protein and CagA co-immunoprecipitated endogenous SHP-2.Results : Tyrosine phosphorylated CagA protein and CagA co-immunoprecipitated endogenous SHP-2 were detected in the gastric mucosa from H. pylori-positive atrophic gastritis patients. All H. pylori strains from these patients were cagA-positive type I strains. After curing H. pylori infection, the tyrosine phosphorylated CagA protein and CagA co-immunoprecipitated endogenous SHP-2 disappeared from the gastric mucosa.Conclusion : The cure of infection reduces the stimulated signal transduction of gastric epithelial cells by the translocated CagA protein of H. pylori, and may confer a beneficial effect on the reduction of cancer risk.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.18.s1.2.x
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  • 9
    Electronic Resource
    Electronic Resource
    Eradication of Helicobacter pylori infection induces an increase in body mass index (2002)
    Oxford UK : Blackwell Science Ltd.
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The relationship between H. pylori infection and body mass indices is controversial.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To investigate the relationship between H. pylori infection and body indices, and to examine the effect of H. pylori eradication therapy on body indices.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:Nine-hundred and thirty-two employees of an industrial corporation were examined for H. pylori infection and body mass indices. Three hundred and two H. pylori-positive cases diagnosed with chronic gastritis by upper gastrointestinal endoscopy or radiography underwent eradication therapy. Body mass indices, serum total cholesterol levels and symptom scores were obtained before and at 12 months after eradication therapy.〈section xml:id="abs1-4"〉〈title type="main"〉Results:There was no significant difference in body weight, body mass index (BMI) or serum total cholesterol level between the H. pylori-positive and H. pylori-negative groups. However, body weight and BMI increased significantly 12 months after eradication of H. pylori infection. In contrast, there was no significant difference in body weight and BMI 12 months after eradication therapy in the non-eradication group. Serum total cholesterol levels did not change after eradication therapy in either the eradication or non-eradication groups.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusion:Eradication of H. pylori infection induced an increase in BMI in industrial workers with chronic gastritis in Japan.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.16.s2.31.x
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  • 10
    Electronic Resource
    Electronic Resource
    The effect of Helicobacter pylori eradication therapy on dyspepsia symptoms in industrial workers in Japan (2001)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The relationship between Helicobacter pylori infection and non-ulcer dyspepsia is still controversial. The potential benefits and risks of the treatment could depend on local conditions, such as the prevalence of the infection and the local rates of gastric cancer.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To evaluate the effects of H. pylori eradication therapy on non-ulcer dyspepsia symptoms in industrial workers in Japan.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:A total of 615 employees of an industrial corporation were examined for H. pylori infection and symptom scores; 215 H. pylori-positive non-ulcer dyspepsia cases underwent eradication therapy. Symptom scores were also analysed 12 months after the eradication therapy. Serum pepsinogen A and pepsinogen C levels were analysed and chronic atrophic gastritis was serologically diagnosed on the basis of the criteria of a pepsinogen A 〈 70 ng/mL and pepsinogen A : pepsinogen C ratio 〈 3.0.〈section xml:id="abs1-4"〉〈title type="main"〉Results:The symptom score improved significantly in the cured cases, but not in the non-cured cases. The effect of the cure of H. pylori infection on symptoms was analysed according to the serological diagnosis of chronic atrophic gastritis. In both groups, cases with atrophic gastritis and cases with chronic gastritis only, the cure of infection was effective in improving symptoms.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusion:The cure of H. pylori infection was effective in reducing non-ulcer dyspepsia symptoms in industrial workers in Japan.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2001.00987.x
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