ISSN:
0173-0835
Keywords:
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Genetic polymorphism of transferrin (Tf) was studied in 473 healthy Swiss blood donors and 236 nonrelated individuals engaged in cases of disputed paternity. Gene frequencies were: TfC1 = 0.7727, TfC2 = 0.1634, TfC3 = 0.0573. Several rare alleles were observed, the frequency of the total of which was 0.0066. Three obviously new Tf alleles were detected. The phenotype distribution was in agreement with the Hardy Weinberg equilibrium. Among 113 mother/child pairs no phenotypes contradictory to the mendelian law were observed. The transferrin system represents a useful parameter in routine paternity testing. Its average chance of exclusion (without rare alleles) is 18.19%.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elps.1150061112
Permalink