ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
From cultures of Gibberella zeae ergosterol, zearalenone (1) and hitherto unknown minor metabolites, i.e.. 5-formyl-zearalenone (6), 7′-dehydrozearalenone (8), 8′-hydroxyzearalenone (9) and 8′-epi-hydroxyzearalenone (11) were isolated. The production of zearalenone and its congeners proved to be very strongly dependent on the conditions of culture.5-Formyl-zearalenone (6) as well as 3-formylzearalenone (4) were synthesized from zearalenone (1) and characterized by the di-O-methyl derivatives 7 and 5 respectively. The structure of 7′- dehydrozearalenone (8) was deduced from spectral data. The di-O-methyl derivatives 10 and 12 respectively of the two corresponding epimeric 8′-hydroxy derivatives 9 and 11 yielded the same β-diketone 13. The keto-enol equilibrium of 13 was studied.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19720550835
Permalink