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  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Long-duration γ-ray bursts (GRBs) are associated with type Ic supernovae that are more luminous than average and that eject material at very high velocities. Less-luminous supernovae were not hitherto known to be associated with GRBs, and therefore GRB–supernovae were thought to be ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Regulatory Peptides 10 (1985), S. 33-38 
    ISSN: 0167-0115
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Regulatory Peptides 10 (1985), S. 182-187 
    ISSN: 0167-0115
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1590-3478
    Keywords: Multiple sclerosis ; peripheral benzodiazepine receptors ; mononuclear cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario In questo studio riportiamo le caratteristiche dei recettori benzodiazepinici di tipo periferico (pBZr) in cellule mononucleate (MNC) isolate dal sangue di pazienti con sclerosi multipla (SM), in fase attiva o stabile, e di controlli normali. Abbiamo osservato una significativa riduzione della densità recettoriale nelle cellule dei pazienti con SM attiva comparati con i controlli, mentre non abbiamo trovato nessuna alterazione in quelle dei pazienti con SM in remissione. Nei pazienti con SM attiva il trattamento steroideo induce una normalizzazione della densità recettoriale e la sospensione è associata con un modesto aumento dei siti di legame rispetto ai controlli. I nostri dati suggeriscono che la densità dei pBZr nelle MNC di pazienti con SM potrebbe variare in relazione sia al decorso clinico che al trattamento con steroidi.
    Notes: Abstract We report here a study of peripheral type benzodiazepine receptors (pBZr) in mononuclear cells (MNC) from blood of patients with multiple sclerosis (MS) during periods of stable and active disease and from normal controls. Most active MS patients were retested in a longitudinal study, both during a treatment with high dose steroids and while medication free. Active MS produces a significant decrease of receptor density compared with the controls whereas remission of the disease shows no effect. Four weeks of steroid treatment restore binding density to normal levels, and two weeks of drug withdrawal result in a small, but significant increase in number of the binding sites compared with the control value. We suggest that the number of pBZr in blood MNC might change during the clinical course and steroid therapy of MS.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 13 (1992), S. 793-796 
    ISSN: 1590-3478
    Keywords: Polyneuropathy ; demyelinating disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Viene presentato un caso in cui ad una sindrome acuta tipo Guillain-Barré è successivamente seguita una malattia demielinizzante centrale, come documentato dal quadro clinico, dalla Risonanza Magnetica Nucleare (RMN), dalle indagini elettrofisiologiche e liquorali. La particolare sequenza temporale della sintomatologia clinica sembra escludere una semplice coincidenza di due malattie distinte e sembra costituire una ulteriore prova di un possibile legame eziologico tra un danno mielinico centrale e periferico. Viene discussa la possibilità che un comune fattore patogenetico possa essere responsabile di demielinizzazione centrale e periferica.
    Notes: Abstract We report a case in which an acute Guillain-Barré-like syndrome was quickly followed by a central demyelinating disease, documented by the clinical findings as well as by magnetic resonance imaging (MRI), electrophysiological and cerebrospinal fluid examinations. The close follow-on of the clinical signs seems to exclude a simple coincidence of two separate diseases and it may constitute further evidence for a possible etiological link between central and peripheral myelin damage. We discuss the possibility of a common pathogenic factor underlying central and peripheral demyelination.
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  • 6
    ISSN: 1432-1238
    Keywords: Total parenteral nutrition ; Nitrogen balance ; Malnourished patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 38 malnourished patients studied for a cumulative period of 280 days. According to multiple regression analysis, nitrogen intake (0.213±0.004 g kg-1 day-1, mean ±SD) proved to be the major determinant of a positive nitrogen balance (0.018±0.004 g kg-1 day-1), followed by non-protein energy intake (43.3±0.5 kcal kg-1 day-1). Total calorie intake to predicted basal energy expenditure and non protein calorie to nitrogen ratios appeared to have little significance on nitrogen balance, when corrected for the two former variables.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Probability theory and related fields 46 (1979), S. 289-298 
    ISSN: 1432-2064
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary Our purpose is to extend the previous work of O. Lanford on microcanonical variational principle [3] to a ℤv action on a compact set satisfying expansivness and specification.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Probability theory and related fields 79 (1988), S. 227-248 
    ISSN: 1432-2064
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Description / Table of Contents: Résumé Nous étudions le comportement asymptotique de produits aléatoires d'opérateurs de Ruelle-Perron-Frobenius. Nous étendons le travail de Ruelle obtenu dans le cas homogène, au cas aléatoire.
    Notes: Summary We study the asymptotic behaviour of random products of Ruelle-Perron-Frobenius operators. We extend the previous work of Ruelle in the homogeneous case to the random case.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 2 (1981), S. 53-57 
    ISSN: 1590-3478
    Keywords: Hemodialysis ; chronic renal failure ; “Disequilibrium syndrome”
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Abbiamo censito e sottoposto ad indagine statistica le complicanze neurologiche acute transitorie insorgenti nel corso di emodialisi in 103 pazienti con insufficienza renale cronica (sono state esaminate 13.969 emodialisi). Dai nostri dati risulta che tali complicanze consistono di una sintomatologia multiforme: parte dei sintomi presentati dai pazienti sono aspecifici (cefalea, nausea e/o vomito, crampi muscolari). Sono presenti in oltre il 96% dei pazienti, associati a sintomi e fenomeni extraneurologici, quali collasso circolatorio o aumento di pressione arteriosa). Altri sintomi denotanti una vera compromissione cerebrale (convulsioni, disturbi di coscienza, agitazione psicomotoria) sono meno frequenti (compaiono nel 36% dei pazienti) e solo il 10,5% dei soggetti presenta un'associazione di almeno due di questi sintomi, configurando una “Sindrome da disequilibrio”, con percentuale, nel nostro campione, analoga a quella riferita in letteratura.
    Notes: Abstract We have examined and subjected to statistical analysis the transient acute neurological complications arising in the course of hemodialysis in 103 patients with chronic renal failure (13,969 hemodialysis sessions). Our data show that such complications are multiform. Some of the symptoms are aspecific: headache, nausea and/or vomiting, muscle cramps. We have found these symptoms in over 96% of patients, often combined with extraneurological symptoms and phenomena, such as cardiocirculatory shock or increased blood pressure. The other symptoms denote real cerebral impairment: convulsions, consciousness disturbances, psychomotor agitation. They are present in 36% of the patients, but only 10.5% of the patients show a combination of at least two symptoms. In these patients the so-called “Disequilibrium syndrome” is present: its percentage in our case-series is similar to that reported in leterature.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 3 (1982), S. 281-287 
    ISSN: 1590-3478
    Keywords: brainstem auditory evoked potentials ; minor head injury ; postconcussion syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario I potenziali evocati acustici del tronco cerebrale (BAEP) sono stati registrati in 55 pazienti affetti da sindrome soggettiva postcraniotraumatica (PCS), per evidenziare un possibile danno organico subclinico del tronco cerebrale. Quindici pazienti (27.3%) hanno mostrato risposte alterate unilateralmente o bilateralmente, soprattutto a causa della presenza di una o più latenze interpicchi oltre i limiti fiduciali superiori del 99%. Altri 9 pazienti hanno mostrato risposte borderline. Non sono state ritrovate correlazioni tra il reperto di BAEP alterati e la presenza di vertigini all'atto dell'esame, né con il comportamento dell'esame vestibolare. Benché le alterazioni del BAEP si possano osservare anche a distanza di molti mesi dal trauma, la maggioranza dei pazienti con BA EP alterati, ad un secondo esame ha mostrato un miglioramento della risposta. Tali dati dimostrano che i BAEP sono in grado, in alcuni pazienti affetti da PCS, di evidenziare un danno organico del tronco cerebrale, passibile di regressione.
    Notes: Abstract Brainstem auditory evoked potentials (BAEPs) were recorded from 55 patients with postconcussion syndrome (PCS) to elicit evidence of an organic and subclinical brainstem disorder. Fifteen patients (27.3%) showed abnormal responses unilaterally or bilaterally, especially for one or more interpeak latencies prolonged beyond the upper 99% confidence limits. Other 9 patients had borderline responses. The BAEP alterations were not correlated either with dizziness at the time of recording, or with vestibular troubles in the routine caloric test. Though BAEP abnormalities may be present a long time after injury, we found an improvement of responses in the majority of 14 re-tested patients. These data show that BAEP can give an objective demonstration of a reversible brainstem disorder in patients with PCS.
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