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  • 1
    Electronic Resource
    Electronic Resource
    Age-related thiamin transport by small intestinal microvillous vesicles of rat
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1105 (1992), S. 271-277 
    Details
    ISSN: 0005-2736
    Keywords: (Rat) ; Aging ; Intestinal transport ; Microvillous membrane vesicle ; Thiamin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0005-2736(92)90204-Y
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  • 2
    Electronic Resource
    Electronic Resource
    Stenting of the extracranial internal carotid artery for dissecting aneurysm (1999)
    Springer
    Italian journal of neurological sciences 20 (1999), S. 251-253 
    Details
    ISSN: 1126-5442
    Keywords: Key words Aneurysm, carotid ; Carotid arteries, dissection ; Stents ; Prostheses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Symptomatic dissecting aneurysms of the extracranial internal carotid artery are not frequent. Medical treatment of these lesions can be ineffective and surgical options present high morbidity. We describe a case successfully treated with endovascular therapy, using a self-expanding stent. The advantages of the endovascular treatment and the rationale of the use of self-expanding stents are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100720050040
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  • 3
    Electronic Resource
    Electronic Resource
    Combined Management of Intracranial Aneurysms by Surgical and Endovascular Treatment. Modalities and Results from a Series of 395 Cases (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 557-562 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Aneurysms; embolization; Guglielmi detachable coil; clinical outcome.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  The selective occlusion of saccular intracranial aneurysms may be achieved by two techniques: microsurgical clipping and endovascular coiling. Each of them have particular indications which need to be defined. We report on a series in which both techniques were applied.  From September 1992 to June 1996, 395 consecutive patients with small or large aneurysm were treated either by surgery (N=102) or by endovascular coiling (N=293). Coiling was chosen each time the shape of the aneurysm seemed to be appropriate for this treatment: narrow neck and ratio neck diameter by sac diameter less than one third.  Satisfactory results with complete or subtotal obliteration and no recanalization on the following controls at 1, 6, 12 and 36 months, were obtained in 92% before retreatment and in 98.8% after retreatment. Unsatisfactory results were observed after surgery in 7 cases and in 25 cases after embolization. After retreatment, it remains 3 post-surgical and 2 post-endovascular cases.  In the overall series, good and excellent clinical outcome was noted in 90% for small aneurysms and in 86.5% for large ones; mortality was of 4.8%.  In a series in which were applied both types of treatment, surgery in 25% and endovascular technique in 75%, good results in terms of aneurysm occlusion and clinical results were achieved. These results are as good as the best series in which surgery was the only choice. Therefore with appropriate selection, endovascular treatment is a good alternative for treatment of the majority of saccular aneurysms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050343
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  • 4
    Electronic Resource
    Electronic Resource
    PC10 monoclonal antibody to proliferating cell nuclear antigen as probe for cycling cell detection in developing tissues (1993)
    Springer
    Histochemistry and cell biology 99 (1993), S. 191-199 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Proliferating cell nuclear antigen (PCNA), also referred to as cyclin, is an auxiliary protein to DNA-polymerase delta and a proposed marker of replicating cells. We have investigated the applicability and limitations of PC10 monoclonal antibody to PCNA in a cell kinetics study of developing human and rat tissues by immunocytochemical and flow cytometric techniques. Our data demonstrate that the epitope recognized by PC10 antibody is resistant to wax embedding, but sensitive to aldehyde fixation; conversely, alcoholic fixative solutions preserve the immunoreactivity to PC10. Tissue distribution, DNA content and bromodeoxyuridine uptake confirm that PC10-immunoreactive cells in alcoholfixed tissues are cycling (G1-, S- and G2-phases traversing) cells. It is concluded that the PC10 antibody can be regarded as a powerful tool to study cell kinetics and differentiation in developing tissues, provided that the tissue processing is adeguate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00269137
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  • 5
    Electronic Resource
    Electronic Resource
    Peptidergic nerves in human dental pulp (1990)
    Springer
    Histochemistry and cell biology 95 (1990), S. 115-121 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The peptidergic innervation of human dental pulp was studied with indirect immunofluorescence and immunoperoxidase techniques. Pulpal nerve fibres displaying immunoreactivity for cholecystokinin, calcitonin gene-related peptide, C-terminal flanking peptide of neuropeptide tyrosine, leucine-enkephalin, methionine-enkephalin, neuropeptide K, neuropeptide tyrosine, peptide with N-terminal histidine and C-terminal isoleucine, somatostatin-28, substance P and vasoactive intestinal polypeptide were observed. Immunoreactive axon varicosities were detectable within radicular and coronal nerve trunks and within the nerve plexus of Raschkow in the para-odontoblastic region. Many peptidergic nerve fibres were observed in association with blood vessels of various sizes. Substance P- and calcitonin-gene-related peptide-immunoreactive axons were visible in the odontoblastic layer. The occurrence of VIP- and PHI-immunoreactive fibres lends support to the hypothesis that human tooth may be supplied by parasympathetic nerves. The immunocytochemical results here shown provide a morphological basis to previous experimental studies concerning the possible roles of neuropeptides in nociception mechanisms, control of the blood flow and modulation of the inflammatory response in dental tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00266583
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  • 6
    Electronic Resource
    Electronic Resource
    A proposed angiographic classification of intracranial arteriovenous fistulae and malformations (1993)
    Springer
    Neuroradiology 35 (1993), S. 381-385 
    Details
    ISSN: 1432-1920
    Keywords: Arteriovenous malformations ; Arteriovenous fistulae ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We propose an angioarchitectural classification of intracranial vascular lesions as arteriovenous, arteriolovenous and arteriolovenulous fistulae. In order to validate this classification, 99 intracranial arteriovenous lesions were reviewed in 98 patients. Arteriolovenulous fistulae included 39 isolated brain arteriovenous malformations (AVMs) and 1 AVM associated with a giant arteriovenous fistula (AVF). Arteriovenous fistulae included 8 giant AVFs of the brain, 6 vein of Galen aneurysms and 10 direct caroticocavernous fistulae. Arteriolovenous fistulae included 1 isolated brain AVM, 4 vein of Galen aneurysms and 30 dural AVMs. The angioarchitectural classification has three advantages. It is simple and accurate, with no reference to the congenital or acquired nature of the lesion. It allows separate identification of a special group, the arteriolovenous fistulae. It also indicates the endovascular approach: arteriolovenulous fistulae should be treated via the arterial route only, while arteriovenous and arteriolovenous fistulae can be treated via transarterial or transvenous approaches.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588376
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  • 7
    Electronic Resource
    Electronic Resource
    Balloon occlusion of the internal carotid artery in 40 cases of giant intracavernous aneurysm: technical aspects, cerebral monitoring, and results (1992)
    Springer
    Neuroradiology 34 (1992), S. 245-251 
    Details
    ISSN: 1432-1920
    Keywords: Cerebral aneurysm ; Endovascular therapy ; Balloon occlusion ; Carotid artery occlusion ; Cerebral blood flow ; Transcranial Doppler sonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have studied the results of carotid occlusion in the treatment of giant intracavernous carotid artery (ICA) aneurysms in 40 patients. Clinical, angiographic, Doppler and cerebral blood flow (CBF) criteria for tolerance of occlusion are discussed. The patients had headaches (47.5%), cranial nerve compression (87.5%), decreased visual acuity (20%), ruptured aneurysm (15%) and 5% were asymptomatic. Balloon occlusion tests were performed under light sedation anaesthesia: a successful test required perfect clinical tolerance and adequate angiographic collateral circulation in arterial, parenchymatous, and venous phases. Additional criteria include xenon 133 CBF measurements, and transcranial Doppler sonography of the middle cerebral artery. According to these criteria, 5 patients did not tolerate test occlusion and required an extra-intracranial (EC-IC) bypass. Mean follow-up was 4.7 years. All patients were radiologically cured of their ancurysm, and in 35 the symptoms resolved, although 3 had persistent ocular motor nerve palsies, and in 4 visual defects were unchanged. Complications were 1 permanent and 3 transient neurological deficits. Balloon occlusion of the ICA is an effective, reliable form of treatment for intracavernous giant aneurysm and should replace surgical ligation of the cervical carotid artery. With CBF or Doppler monitoring, the risk of neurological deficit is diminished. EC-IC bypass prior to ICA occlusion is indicated if test occlusion is not tolerated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596347
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  • 8
    Electronic Resource
    Electronic Resource
    Long-term changes in intracranial dural arteriovenous fistulae leading to worsening in the type of venous drainage (1997)
    Springer
    Neuroradiology 39 (1997), S. 59-66 
    Details
    ISSN: 1432-1920
    Keywords: Key words Arteriovenous fistula dural ; Embolisation ; Haemorrhage ; Subarachnoid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We review seven patients with intracranial dural arteriovenous fistulae (ICDAVF), each altering the initial type of venous drainage to one with a higher grading during long-term follow-up. Five were discovered due to symptoms of intracranial hypertension, two due to changes in tinnitus and one case following subarachnoid haemorrhage. In five cases, cortical venous drainage developed during the follow-up period. Three different mechanisms were observed: stenosis or thrombosis in the draining veins in 4 cases: increased arterial flow in 2; and the appearance o a new fistula site or extension of the initial shunt in 2. Type I and type II a fistulae which are not completely cured, require both close clinical observation and Doppler examinations in the follow-up period. Any charge in the clinical pictures indicates a repeat angiogram. Stenosis of the venous drainage, forecasting later worsening in the venous outlet, requires more thorough angiographic follow-up.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050368
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  • 9
    Electronic Resource
    Electronic Resource
    Therapeutic approach to arteriovenous malformations of the tongue (1998)
    Springer
    European radiology 8 (1998), S. 280-285 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Arteriovenous malformation ; Tongue ; Embolization ; Interventional procedure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Arteriovenous malformations (AVM) are developmental errors with a high complication rate because they are hemodynamically active. The aim of our study is to evaluate management of the rare subgroup of tongue AVM. From 1982 to 1994, 25 patients with AVM of the tongue presented to our department. All patients were discussed in our multidisciplinary staff consultation and were treated by embolization, surgery, or were followed-up clincally with no intervention. Thirteen patients were asymptomatic in a hemodynamically quiescent phase and did not require any kind of intervention. The 12 others underwent embolization procedures following which 6 became stable, 2 had complementary surgery, 1 was lost to follow-up, 1 had two minor bleeding episodes without the need for hospitalization, and 2 were improved. Arteriovenous malformations of the tongue must be followed clinically and treated only if they become active. Permanent embolization with a polymerizing liquid administered through supra-selective catheterization or by direct puncture of the malformation is recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050380
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  • 10
    Electronic Resource
    Electronic Resource
    Lymphatic vessels of the human dental pulp in different conditions (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 234 (1992), S. 27-33 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The characteristics of the lymphatic vessel endothelial wall have been investigated in human normal and inflamed dental pulps. In normal pulps the endothelial wall is characterized by the presence of micropinocytotic vesicles and intraparietal channels. In the inflamed pulpal tissue, where an increase in interstitial fluid pressure occurs, the distended endothelial wall presents open junctions between endothelial cells and the openings of the intraparietal channels. Moreover the micropinocytotic vesicles disappear. The cytoplasm of the endothelial cells is characterized by the presence of numerous Weibel-Palade bodies, which increase in number in the dilated vessels. In the fibrillar apparatus surrounding the lymphatic vessel wall collagen fibrils are the prevalent component, while elastic fibers are not present.The different morphological properties of the lymphatic vessels are compared and discussed with regard to the variation of the functional conditions of the tissue. © 1992 Wiley-Liss, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092340104
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